Twist Bioscience (TWST) logo

Twist Bioscience (TWST) stock

Synthetic DNA , market cap $8.0B

$132.13
-2.37%

As of Tuesday's close · Live for Pro members at the open

Why is TWST down?

Down 24% from Oct 28 to Nov 10.

  • Twist Bioscience fell 24% from Oct 28 to Nov 10. 14 points of it came on Nov 2.

Sources: Price history, Nov 10, 2026

Tell me next time TWST moves

Free account, no card. An optional alert when TWST moves or its score changes.

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1 more reason, free with an account →How the business stands, the timeline, and its peers, for Pro members.

Why TWST still beats the market over three years

Up 716% over the three years to Nov 9 while the S&P 500 rose 80%; down 24% since Oct 28.

7 reasons, from its filings, with the timeline, for Pro members.

Quality Score
1
Below Average
In its industry
#118of 281
Checks firing
0of 14
Choppy
From 52-week high
-39.9%
under its best in a year

TWST's Quality Score fell 2 points on Tue, Nov 10, to 1. It closed away from its high of the day (2 chart checks stopped).

See TWST's 14 chart checksSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Key facts on TWST

Key facts on TWST
Holding it backMoves 11.9% a day with no profit behind it
Latest filing424B7, Aug 19 Priced a sale of shares
1 more reason behind TWST's 1, free with an account →4 more reasons behind TWST's 1, for Pro members.

TWST in the news

ReportReports Thursday, before the open. Every 3 months, a company tells everyone how much it sold and earned. It rose after 2 and fell after 2 of its last 4 reports, +1.8% on average. Past reports ›

What's next

Tue Nov 17: Jefferies 17th Annual London Global…Investor conference · date confirmed.

1 more date ahead: the conference, for Pro members.

TWST catalysts

Coming up

After its last 4 reports it closed +1.8% on average, higher 2 of 4 times.

29 past catalysts since 2019, with sizes and sources, for Pro members.

Why TWST scores 1

Below Averagefor quality, not price, 0 of 14 chart checks firingWhat the Quality Score means

  • +2Long-term trend above a rising 200-⁠day average
  • +2Run-up 337% over 12 months
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Growth addsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.
  • Insider trades subtracts

No effect today: Chart checks, Size, Dilution, Persistence, and News.

What every line is worth, and the reason behind it, on TWST and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:29 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How TWST ranks in Biotech

TWST is #118 of 281 by Quality Score.

How TWST ranks in Biotech
RankStockQuality Score
118Twist Bioscience (TWST) logoTWSTTwist Bioscience1

Net income over four quarters: TWST -$137M, ADPT -$70.5M.

More in Biotech

When does TWST report earnings, and what happens after?

Reports Thu Nov 12, before the open (in 2 days). Confirmed.

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What TWST reported on Aug 3, 2026

The quarter

The figures are not read from the release yet.

The filing on EDGAR

Where the sales came from

TWST's results filing gives no sales by line in a table we read.

The outlook

The outlook the company gave, by period
MeasureFigure
FY2026
Total revenue$456M to $457Mraised

Figures as filed (SEC filing, Aug 3)

3 more outlook lines, for Pro members.

The numbers

Market value
$8B
today
Sales
$432M
up 19.2% on the year
Free cash flow
-$93.1M
last 12 months

Sales grew 33% a year over 5 years, fiscal 2020 to 2025.

Its share count grew 8.8% a year over 5 years.

3 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on TWST: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+14.0%-7.0%+10.4%
Feb 2May 4Aug 3
ReportedGapReaction5
days
Aug 3, 2026Before open-10.9%+10.4%+26.4%
May 4, 2026Before open-2.0%-7.0%-5.9%
Feb 2, 2026Before open+5.8%+14.0%+19.9%

TWST closed higher after 2 of its last 4 reports.

All 4 reports, and TWST's Quality Score going into each

Everyone reporting earnings this week

TWST sales and profit by year

Sales and profit by year

Sales grew every year from 2018 to 2025, to $377M. It lost money in each of the eight years.

Nothing is firing on TWST right now

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on TWST, and all 14 on every stock.Get in free →

TWST RSI today: 44.6, below its 50-day, above its 200-day

Not scored

RSI 44.6, MACD below signal, below its 50-day, above its 200-day. Not scored.

The deep dive on TWST

  • What it does and how it makes money5 findingsAn operating loss of $136M in fiscal 2025, on $377M of sales.Annual report, filed Nov 17, 2025
  • Where it stands2 findingsFor Pro members2 findings on where TWST stands: its cash, debt, and share count, for Pro members
  • What changed in its filings3 findings"Twist Bioscience Corporation, et al., Case No. 22-cv-08168 (N.D. Cal.) ('Securities Class Action') was filed in federal court in the Northern District of California ('Court') against the Company …" (10-Q for the quarter to Jun 30, 2026)SEC filing · Aug 3, 2026New in its "Risk Factors" this year: "Additionally, we compete with both large and emerging providers in the life sciences tools and diagnostics industries focused on sample preparation for NGS such as Thermo Fisher Scientific Inc., Illumina, Inc., Integrated DNA Technologies, Inc., Roche Holding AG, New England Bioloabs, Inc., Watchmaker Genomics …" (10-K for fiscal 2025)SEC filing · Nov 17, 2025Backlog rose 63% in a year, to $21.9M on Jun 30, 2026 from $13.4M: sales under contract, not yet delivered.Filed figures, Jun 30, 2026
  • Who holds and trades it3 findingsFor Pro members3 findings on who holds and trades TWST, for Pro members
  • Against its closest peers1 peerNet income over four quarters: TWST -$137M, ADPT -$70.5M.

9 more findings on TWST, each with its source, for Pro members.

TWST share count over time

Shares: 4.0% more than a year ago (to Jun 30).

Shares of TWST outstanding, as filed
Shares
outstanding
As
of
62.7MJul 29, 2026
62.3MApr 29, 2026
61.3MJan 27, 2026
61.1MNov 13, 2025
Offerings, shelves, and splits of TWST, from its filings
From its
filings
Filed
Priced a sale of sharesAug 19, 2026
Raised $300M in a sale of shares, about 4% of its market valueAug 5, 2026
Registered shares for a later sale (S-3ASR)Jun 18, 2026

TWST insider trades

7 insiders sold $20.8M across 51 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellEmily M. Leproust$619KChief Executive Officerat $135.40 on Nov 3, filed Nov 5

All 51 insider filings on TWST from the last six months, for Pro members.

All TWST insider trades

TWST's officers and directors

Officers and directors with a Form 4 in the last 12 months.

5 more officers and directors file at TWST.

See insider trades by person

Which ETFs hold TWST?

In ETFs: TWST is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Twist Bioscience

Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.

979 employeesSouth San Francisco, CAtwistbioscience.com

What Twist Bioscience says it competes with

“The synthetic biology industry is intensely competitive and is characterized by price competition, technological change, international competition, product turnaround time and manufacturing yield problems.”

From its annual report, SEC filing · Nov 17, 2025

Here is what Pro members see.

  • The same page for Pro members, on Microsoft

    Its Quality Score and rank, the line that drives it, and the live price.

  • The full chart

    A year of candles to start, out to the whole history, with insider trades marked and the Quality Score under the price.

  • Every line of the score

    Price action, the company, and signals, each with its points, on TWST and every other stock.

  • CEOs buying their own stock

    Every CEO buy, biggest names first. Sort, filter, save the list, and set optional alerts.

  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • FDA dates, counted down

    Each date in the company's words, its cash against the date, and an optional alert before it.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

  • The top 10, every day

    The ten highest Quality Scores at each close, kept day by day, week by week.

  • Optional alerts, your way

    Pick a stock, a score, a price, a filing, or a whole scan. It tells you by push or email.

  • Your watchlist, scored

    Your stocks by Quality Score, today's move, or name.

  • On your phone and your laptop

    The same account and watchlist on both, each laid out for its screen.

  • Prices refresh every 2.5 seconds during market hours.
  • Optional alerts by push, email, or the bell.
  • Add it to your Home Screen and it opens like an app.

Pro members see every line of every stock's score.

  • What would turn TWST's score around: 7 things
  • 4 more filings explained, a plain line each
  • Real-⁠time prices, no delay
BreakawayNov 5Emily M. Leproust sold TWST$619K at $135.40, filed Nov 5

Alerts are optional.

See TWST's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: TWST's Quality Score is 1 (Below Average), #118 of 281 in Biotech. Insiders sold $20.8M in the last 6 months (Form 4).

What does TWST's Quality Score say?

TWST scores 1 today, which Breakaway calls Below Average. It is #118 of 281 in Biotech by Quality Score, with 0 of 14 chart checks firing. Down 24% from Oct 28 to Nov 10. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is TWST's Quality Score?

TWST scores 1 today, which Breakaway calls Below Average (0 to 5). That is #118 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind TWST's 1.

Are insiders buying TWST?

7 insiders sold $20.8M across 51 filings in the last 6 months. No open-⁠market buys on record. The newest is Emily M. Leproust, Chief Executive Officer, who sold $619K on Nov 3. Every filing, with the scored weight, for Pro members.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

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Insider and Congress trades, the chart, and the financials, in one score.

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The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

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