BeOne Medicines (ONC) logo

BeOne Medicines (ONC) stock

Oncology therapeutics , market cap $44B

Pre-market
$408.96
+0.49%

Close $406.96 +5.09%

As of 8:42 AM ET pre-market, delayed 15+ min · Live for Pro members

Quality Score
22
Exceptional
In its industry
#2of 281
Checks firing
6of 14
Trending up
From 52-week high
-0.9%
under its best in a year

ONC's Quality Score rose 1 point on Fri, Nov 6, to 22. Its 6-month gain reached 30%.

Follow ONC's trial news. Pro members can get an alert when BeOne Medicines files news, and see its trials, share raises, and its CEO's filings.

Get an alert when ONC files news on its trialsSee it live, free until tomorrow morning. No account. No card. Then keep going with a free account.

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NextDec 31, 2026 · In 52 daysPhase 3 main data due · ClinicalTrials.gov · Aug 28

Why is ONC up?

Up 15% from Nov 3 to Nov 6 while the S&P 500 fell 3%.

“The gross margin percentage increased due to a proportionally higher sales mix of global BRUKINSA compared to other products in the Company’s portfolio.”

BeOne Medicines' Nov 5 release said

Sources: Price history, Nov 6, 2026; Company release, Nov 5, 2026

1 more reason, free with an account →4 more reasons why ONC rose 15% since Nov 3, from its filings, with the company's words, the timeline, and its peers, for Pro members.

Key facts on ONC

Key facts on ONC
SalesUp 56% a year for 3 years vs 5% for its peers
Latest filing8-K, Nov 5 Reported its quarterly results
1 more reason behind ONC's 22, free with an account →5 more reasons behind ONC's 22, for Pro members.

ONC in the news

What's next

Tue Nov 17: Jefferies 17th Annual London Global…Investor conference · date confirmed.

1 more date ahead: the conference, for Pro members.

ONC catalysts

Coming up

After its last 4 reports it closed +0.2% on average, higher 3 of 4 times.

8 past catalysts since 2025, with sizes and sources, for Pro members.

What's next for ONC

Next Phase 3 data on the registry

Dec 31In 52 daysPhase 3 main data due for Zanubrutinib, Dec 31, 2026Phase 3 main data due · ClinicalTrials.gov · Aug 28

What it means: the date the registry lists for the trial’s last main measurement, as the sponsor estimates it. Results usually follow weeks to months later.

Lead program
Zanubrutinib
Another trial
Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell Malignancies Who Participated in BeiGene Parent Studies of ZanubrutinibPhase 3 · Active · 955 people · main data estimated Dec 31, 2026 · NCT04170283

56 more trials, 5 with data due this year, 6 drugs past Phase 1, 1 drug news item, and 46 filings, for Pro members.

Dilution on the horizon

No shelf registration or at-the-market program on file in the last three years.

For Pro members: 1 raise and its amount, and the share count against a year ago.

Insiders

Director Xiaodong Wang sold 31,028 shares on Oct 27, under a planned sale. 45 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and John Oyler’s 26 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why ONC scores 22

Exceptionalfor quality, not price, 6 of 14 chart checks firingWhat the Quality Score means

Well above its recent run. ONC scores 22 today, against a median of 15.5 over its last 20 recorded sessions.

  • +6Chart checks 6 of 14 firing right now, one point each
  • +4Long-term trend above a rising 200-⁠day average, near its 52-⁠week high, at a multi-⁠year high
  • Run-up adds
  • Size adds
  • Profit addsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Growth addsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Persistence adds
  • News adds

No effect today: Dilution, Volatility, Cash flow, and Insider trades.

What every line is worth, and the reason behind it, on ONC and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 8:42 AM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How ONC ranks in Biotech

ONC is #2 of 281 by Quality Score.

How ONC ranks in Biotech
RankStockQuality Score
2BeOne Medicines (ONC) logoONCBeOne Medicines22

Net income over four quarters: ONC $916M, JAZZ $941M, RPRX $672M, TGTX $441M.

More in Biotech

When does ONC report earnings, and what happens after?

Expected to report Thu Feb 25, before the open (in 108 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What ONC reported on Nov 5, 2026

The quarter

Sales of $1.9B, 34% more than a year ago; a profit of $3.28 a share.

“The gross margin percentage increased due to a proportionally higher sales mix of global BRUKINSA compared to other products in the Company’s portfolio.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

Where the quarter's sales came from
LineQ3
2026
Q2
2026
Q3
2025
By product
Productup 33%$1.9B98%$1.7B99%$1.4B99%

Each quarter's sales and their share of its total. Figures as filed (SEC filing, Nov 5)

12 more lines, for Pro members.

The outlook

The outlook the company gave, by period
MeasureFigure
FY 2026
Total revenue$6.9B to $7.0Braised

Figures as filed (SEC filing, Nov 5)

5 more outlook lines, for Pro members.

In the company's words

  • “GAAP net income for the third quarter of 2026 was $385 million, an increase of $260 million over the prior-year period, primarily attributable to revenue growth and improved operating leverage.”

From its results filing (SEC filing · Nov 5)

The numbers

Market value
$44B
today
Sales
$6.6B
up 32.9% on the year
Free cash flow
$1.4B
last 12 months

Sales grew 77% a year over 5 years, fiscal 2020 to 2025.

Its share count grew 6.3% a year over 5 years.

5 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on ONC: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+5.3%+1.4%+2.5%
May 6Aug 5Nov 5
ReportedGapReaction5
days
Nov 5, 2026Before open+5.6%+2.5%not yet
Aug 5, 2026Before open+1.9%+1.4%+11.2%
May 6, 2026Before open+3.0%+5.3%+5.9%

ONC closed higher after 3 of its last 4 reports.

All 4 reports, and ONC's Quality Score going into each

ONC sales and profit by year

Sales and profit by year

Sales grew in six of the last seven years, to $5.3B in 2025. It turned a profit in 2025 after a loss in 2024.

ONC has 6 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on ONC, and all 14 on every stock.Get in free →

ONC RSI on Nov 6: 68.0, above its 50-day and 200-day averages

Not scored

RSI 68.0, MACD above signal, above both averages. Not scored.

The deep dive on ONC

  • What it does and how it makes money4 findings"A significant portion of our rights to receive certain tiered mid-single digit royalty payments based on annual net revenue from sales outside of China of IMDELLTRA were sold to Royalty Pharma in the third quarter of 2025." (10-K for fiscal 2025)SEC filing · Feb 26, 2026
  • Where it stands4 findingsFor Pro members4 findings on where ONC stands: its cash, debt, and share count, for Pro members
  • What changed in its filings6 findings"On February 25, 2026, our subsidiaries, BeOne Medicines USA Inc. and BeOne Medicines I GmbH, filed a patent infringement suit under the Hatch-Waxman Act against Zydus Pharmaceuticals (USA) Inc. and Zydus Lifesciences Limited (collectively, 'Zydus') in the United States District Court for the District of New Jersey." (10-Q for the quarter to Sep 30, 2026)SEC filing · Nov 5, 2026A new heading in its "Risk Factors" this year: "Federal legislative and regulatory efforts to implement reference pricing or most-favored-nation pricing models could impact our product revenues and materially harm our business." (10-K for fiscal 2025; not in fiscal 2024's)SEC filing · Feb 26, 2026, against the one of Feb 27, 2025ASD Specialty Healthcare made up 18% of its revenue in fiscal 2025, up from 18% in fiscal 2024.SEC filing · Feb 26, 2026
  • Who holds and trades it2 findingsFor Pro members2 findings on who holds and trades ONC, for Pro members
  • Against its closest peers4 peersNet income over four quarters: ONC $916M, JAZZ $941M, RPRX $672M, TGTX $441M.

12 more findings on ONC, each with its source, for Pro members.

ONC share count over time

Shares: 3.2% more than a year ago (to Sep 30).

Shares of ONC outstanding, as filed
Shares
outstanding
As
of
1.48BOct 30, 2026
1.48BJul 31, 2026
1.45BApr 30, 2026
1.44BFeb 13, 2026
Offerings, shelves, and splits of ONC, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)May 6, 2026
Priced a sale of sharesMar 10, 2025

ONC insider trades

10 insiders sold $8M across 38 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellTitus B. Ball$47KPrincipal Accounting Officerat $355.86 on Sep 1, filed Sep 3

All 38 insider filings on ONC from the last six months, for Pro members.

All ONC insider trades

ONC's officers and directors

Officers and directors with a Form 4 in the last 12 months.

11 more officers and directors file at ONC.

See insider trades by person

About BeOne Medicines

Formerly known as BeiGene and founded in 2010 in Beijing, BeOne is a commercial-stage biotech firm that produces oncology therapeutics. The company's main product is Brukinsa, which is a small-molecule drug that treats multiple forms of non-Hodgkin lymphoma and leukemia. The company conducts drug discovery, runs global clinical trials, and manufactures drugs independently. As of 2025, Brukinsa made up 74% of total revenue, while it has two other approved commercialized drugs in its portfolio, Beqalzi and Tevimbra. While Brukinsa has global leadership, the other two drugs generate revenue mostly from China. Based on Brukinsa, BeOne competes mainly with AbbVie and AstraZeneca. The company also has more than 50 drugs in clinical trials in its active pipeline, focused on other cancers.

12,000 employeesBaselbeonemedicines.com

What BeOne Medicines says it competes with

“We operate in a highly competitive global landscape, with our marketed products facing strong competition in regulated markets worldwide.”

From its annual report, SEC filing · Feb 26, 2026

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  • What would move ONC's score: 2 things
  • 4 more filings explained, a plain line each
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BreakawaySep 3Titus B. Ball sold ONC$47K at $355.86, filed Sep 3

Alerts are optional.

See ONC's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 9, 2026: ONC's Quality Score is 22 (Exceptional), #2 of 281 in Biotech. Insiders sold $8M in the last 6 months (Form 4).

What does ONC's Quality Score say?

ONC scores 22 today, which Breakaway calls Exceptional. It is #2 of 281 in Biotech by Quality Score, with 6 of 14 chart checks firing. Up 15% from Nov 3 to Nov 6 while the S&P 500 fell 3%. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is ONC's Quality Score?

ONC scores 22 today, which Breakaway calls Exceptional (20 or more). That is #2 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind ONC's 22.

Are insiders buying ONC?

10 insiders sold $8M across 38 filings in the last 6 months. No open-⁠market buys on record. The newest is Titus B. Ball, Principal Accounting Officer, who sold $47K on Sep 1. Every filing, with the scored weight, for Pro members.

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What's next for BeOne Medicines: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

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