Oruka Therapeutics (ORKA) logo

Oruka Therapeutics (ORKA) stock

Psoriasis medicines , market cap $6.4B

Pre-market
$103.51
+0.63%

Close $102.86 +7.12%

As of 8:53 AM ET pre-market, delayed 15+ min · Live for Pro members

Quality Score
7
Average
In its industry
#59of 281
Checks firing
8of 14
Trending up
From 52-week high
-11.0%
under its best in a year

ORKA's Quality Score rose 4 points on Fri, Nov 6, to 7. Buying reached its highest in 20 days (4 chart checks started).

Follow ORKA's trial news. Pro members can get an alert when Oruka Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an alert when ORKA files news on its trialsSee it live, free until tomorrow morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextDec 2026“of 3Q 2026; 52-week data for all participants expected in December 2026”Trial data · SEC filing · Aug 10
Cash$874M, Over 5 years at the last year's spendingOn Jun 30

Why is ORKA up?

Up 28% from Oct 23 to Nov 6 while the S&P 500 fell 3%.

  • Oruka Therapeutics rose 28% from Oct 23 to Nov 6 while biotech stocks rose a median 2%: it beat its group by 26 points.

Sources: Price history, Nov 6, 2026

1 more reason, free with an account →1 more reason why ORKA rose 28% since Oct 23, from its filings, with how the business stands, the timeline, and its peers, for Pro members.

Key facts on ORKA

Key facts on ORKA
OutperformingUp 277% in a year vs the S&P's +9%
Latest filingS-3, Aug 21 Registered shares for a later sale (S-3)
1 more reason behind ORKA's 7, free with an account →4 more reasons behind ORKA's 7, for Pro members.

ORKA in the news

ReportExpected to report Wednesday, before the open. Every 3 months, a company tells everyone how much it sold and earned. It rose after 2 and fell after 2 of its last 4 reports, +4.0% on average. Past reports ›

Big story

Mon Oct 26: Trial

Oruka reports positive phase 2b psoriasis trial results By Investing.com

ORKA closed +12.7% that day on 2.1x normal volume.

Reported by investing.com nigeria · covered by 4 outlets

What's next

Tue Nov 10: Guggenheim 3rd Annual Global…Investor conference · date confirmed.

3 more dates ahead: conferences, for Pro members.

Cash$874M, Over 5 years at the last year's spendingOn Jun 30

ORKA catalysts

Coming up

After its last 4 reports it closed +4.0% on average, higher 2 of 4 times.

3 past catalysts since 2019, with sizes and sources, for Pro members.

What's next for ORKA, and how long its cash lasts

Next step the company has named

Dec 2026“of 3Q 2026; 52-week data for all participants expected in December 2026”Trial data · SEC filing · Aug 10

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque PsoriasisPhase 2 · Active · 160 people · main data estimated Oct 2027 · NCT07474792

4 more trials, 2 more milestones and 34 filings, for Pro members.

Cash runway Jun 30 balance sheet

Over 5 years

$874M in cash and short-term investments, at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money.

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

No shelf registration or at-the-market program on file in the last three years.

For Pro members: 2 raises and their amounts, and the share count against a year ago.

Insiders

CEO Lawrence Otto Klein sold 25,000 shares on Nov 2, under a planned sale. 41 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Lawrence Klein’s 9 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why ORKA scores 7

Averagefor quality, not price, 8 of 14 chart checks firingWhat the Quality Score means

Well above its recent run. ORKA scores 7 today, against a median of 2.5 over its last 20 recorded sessions.

  • +8Chart checks 8 of 14 firing right now, one point each
  • +2Long-term trend above a rising 200-⁠day average
  • Run-up adds
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Dilution subtractsNew shares over the year: -1 at 10% more, -2 at 25% more.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Size, Growth, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on ORKA and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 8:53 AM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How ORKA ranks in Biotech

ORKA is #59 of 281 by Quality Score.

How ORKA ranks in Biotech
RankStockQuality Score
59Oruka Therapeutics (ORKA) logoORKAOruka Therapeutics7

Cash and short-term investments: ORKA $874M, VRDN $982M, IRON $718M, EWTX $72.3M.

More in Biotech

When does ORKA report earnings, and what happens after?

Expected to report Wed Nov 11, before the open (in 2 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What ORKA reported on Aug 10, 2026

The quarter

The figures are not read from the release yet.

“Other income, net was $8.9 million for the second quarter of 2026, compared to $3.9 million for the second quarter of 2025, driven primarily by interest earned on higher cash and marketable securities.”

The filing on EDGAR

Where the sales came from

ORKA's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The Company expects that its cash, cash equivalents, and marketable securities will be sufficient to fund operations through an anticipated BLA filing for ORKA-001 and continued development of ORKA-002.”

From its results filing (SEC filing · Aug 10)

The numbers

Market value
$6.4B
today

No analyst estimates on Breakaway: every figure here is filed.

The whole report on ORKA: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+25.0%-8.5%+6.4%
Mar 12Apr 30Aug 10
ReportedGapReaction5
days
Aug 10, 2026Before open-2.3%+6.4%+12.4%
Apr 30, 2026After close+0.5%-8.5%-6.3%
Mar 12, 2026After close+2.7%+25.0%+21.4%

ORKA closed higher after 2 of its last 4 reports.

All 4 reports, and ORKA's Quality Score going into each

Everyone reporting earnings this week

ORKA has 8 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on ORKA, and all 14 on every stock.Get in free →

ORKA RSI on Nov 6: 66.6, above its 50-day and 200-day averages

Not scored

RSI 66.6, MACD above signal, above both averages. Not scored.

The deep dive on ORKA

5 more findings on ORKA, each with its source, for Pro members.

ORKA share count over time

13 times the count a year earlier.

Weighted shares, quarter to Jun 30, 2025, both from one filing

Shares of ORKA outstanding, as filed
Shares
outstanding
As
of
66.2MJul 31, 2026
60.3MApr 30, 2026
49.5MFeb 28, 2026
48.4MOct 31, 2025
Offerings, shelves, and splits of ORKA, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3)Aug 21, 2026
Raised $700.4M in a sale of shares, about 11% of its market valueApr 29, 2026
Registered shares for a later sale (S-3)Apr 2, 2026
Set up an at-the-market program for up to $200M of shares, about 3% of its market valueNov 5, 2025

ORKA insider trades

4 insiders sold $301M across 7 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellLawrence Otto Klein$235KChief Executive Officerat $95.71 on Sep 15, filed Sep 15

All 7 insider filings on ORKA from the last six months, for Pro members.

All ORKA insider trades

ORKA's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold ORKA?

In ETFs: ORKA is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Oruka Therapeutics

Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.

68 employeesMenlo Park, CAorukatx.com

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  • What would move ORKA's score: 7 things
  • 8 more filings explained, a plain line each
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BreakawaySep 15Lawrence Otto Klein sold ORKA$235K at $95.71, filed Sep 15

Alerts are optional.

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Straight AnswersStraight Answers

As of Nov 9, 2026: ORKA's Quality Score is 7 (Average), #59 of 281 in Biotech. Insiders sold $301M in the last 6 months (Form 4).

What does ORKA's Quality Score say?

ORKA scores 7 today, which Breakaway calls Average. It is #59 of 281 in Biotech by Quality Score, with 8 of 14 chart checks firing. Up 28% from Oct 23 to Nov 6 while the S&P 500 fell 3%. Cash lasts over 5 years at its spending (to Jun 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is ORKA's Quality Score?

ORKA scores 7 today, which Breakaway calls Average (6 to 10). That is #59 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind ORKA's 7.

Are insiders buying ORKA?

4 insiders sold $301M across 7 filings in the last 6 months. No open-⁠market buys on record. The newest is Lawrence Otto Klein, Chief Executive Officer, who sold $235K on Sep 15. Every filing, with the scored weight, for Pro members.

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What's next for Oruka Therapeutics: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

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