Xeris Biopharma Holdings (XERS) logo

Xeris Biopharma Holdings (XERS) stock

Endocrine medicines , market cap $2.4B

Pre-market
$15.19
-0.07%

Close $15.20 +16.21%

As of 8:42 AM ET pre-market, delayed 15+ min · Live for Pro members

Quality Score
22
Exceptional
In its industry
#1of 281
Checks firing
9of 14
Trending up
From 52-week high
-0.1%
under its best in a year

XERS's Quality Score fell 1 point on Mon, Nov 9, to 22.

Follow XERS's news. Pro members can get an alert when Xeris Biopharma Holdings files news, and see its trials, share raises, and its CEO's filings.

Get an alert when XERS files newsSee it live, free until tomorrow morning. No account. No card. Then keep going with a free account.

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NextEnd of 2026“We remain on track to initiate Cornerstone, our pivotal Phase 3 study, by year-end.”Trial start · SEC filing · Nov 5

Why is XERS up?

Up 50% from Nov 2 to Nov 6 while the S&P 500 fell 2%.

  • Xeris Biopharma rose 50% from Nov 2 to Nov 6. 26 points of it came on Nov 5, the day of its results.

Sources: Price history, Nov 6, 2026; SEC filing, Nov 5, 2026

1 more reason, free with an account →3 more reasons why XERS rose 50% since Nov 2, from its filings, with the company's words, the timeline, and its peers, for Pro members.

Key facts on XERS

Key facts on XERS
Operating marginUp 14.9 points on the year
Its scoreUp:Highest Quality Score since Aug 2025 Scores before Sep 10, 2026 were rebuilt.
Latest filing8-K, Nov 5 Reported its quarterly results
1 more reason behind XERS's 22, free with an account →4 more reasons behind XERS's 22, for Pro members.

XERS in the news

ThuXeris Biopharma Holdings, Inc. Q3 2026 Earnings Call Summary Yahoo Finance and 2 more

Outlet counts from the GDELT Project.

What's next

Mon Nov 16: Jefferies 17th Annual London Global…Investor conference · date confirmed.

1 more date ahead: the conference, for Pro members.

XERS catalysts

Coming up

After its last 4 reports it closed +4.6% on average, higher 2 of 4 times.

7 past catalysts since 2025, with sizes and sources, for Pro members.

What's next for XERS

Next step the company has named

End of 2026“We remain on track to initiate Cornerstone, our pivotal Phase 3 study, by year-end.”Trial start · SEC filing · Nov 5

What it means: when a trial begins, or reaches the stage the company named.

For Pro members: 2 more milestones and 33 filings.

Dilution on the horizon

  • Shelf registration (S-3, filed Mar 6, 2025)
  • At-the-market share sales program (S-3, filed Mar 6, 2025)

For Pro members: the amounts, and the share count against a year ago.

Insiders

An officer, Kevin McCulloch, sold 25,000 shares on Nov 5, under a planned sale. 29 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and John Shannon Jr’s 7 filings and quotes.

Get an alert when XERS files newsA free account. No card.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why XERS scores 22

Exceptionalfor quality, not price, 9 of 14 chart checks firingWhat the Quality Score means

Well above its recent run. XERS scores 22 today, against a median of 14.5 over its last 20 recorded sessions.

  • +9Chart checks 9 of 14 firing right now, one point each
  • +4Long-term trend above a rising 200-⁠day average, near its 52-⁠week high, at a multi-⁠year high
  • Run-up adds
  • Growth addsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Persistence adds
  • News adds

No effect today: Size, Profit, Dilution, and Cash flow.

What every line is worth, and the reason behind it, on XERS and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 8:42 AM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How XERS ranks in Biotech

XERS is #1 of 281 by Quality Score.

How XERS ranks in Biotech
RankStockQuality Score
1Xeris Biopharma Holdings (XERS) logoXERSXeris Biopharma22

Share count against a year before: XERS +8.4%, RCUS +19%.

More in Biotech

When does XERS report earnings, and what happens after?

Expected to report Thu Mar 4, before the open (in 115 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What XERS reported on Nov 5, 2026

The quarter

Sales of $107.2M, 44% more than a year ago; a profit of $0.06 a share.

“The increase was primarily driven by increased patient demand for Recorlev.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

XERS's results filing gives no sales by line in a table we read.

The outlook

The outlook the company gave, by period
MeasureFigure
Full year 2030
Total revenuemore than $1 billionraised

Figures as filed (SEC filing, Nov 5)

In the company's words

  • “We now see Recorlev on a path to nearly $1 billion in annual net revenue three to four years sooner than previously expected.”

From its results filing (SEC filing · Nov 5)

The numbers

Market value
$2.4B
today
Sales
$335M
up 36.3% on the year

Sales grew 38% a year over 3 years, fiscal 2022 to 2025.

Its share count grew 8.4% a year over 3 years.

3 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on XERS: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+4.1%-9.3%+25.1%
May 7Aug 6Nov 5
ReportedGapReaction5
days
Nov 5, 2026Before open+19.6%+25.1%not yet
Aug 6, 2026Before open-11.3%-9.3%+4.7%
May 7, 2026Before open+5.2%+4.1%+0.9%

XERS closed higher after 2 of its last 4 reports.

All 4 reports, and XERS's Quality Score going into each

XERS sales and profit by year

Sales and profit by year

Sales grew every year from 2020 to 2025, to $292M. It turned a profit in 2025 after a loss in 2024.

XERS has 9 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on XERS, and all 14 on every stock.Get in free →

XERS RSI on Nov 6: 82.4, above its 50-day and 200-day averages

Not scored

RSI 82.4, MACD above signal, above both averages. Not scored.

The deep dive on XERS

  • What it does and how it makes money5 findingsIt kept 9 cents of each dollar of sales in fiscal 2025: $24.9M of operating profit on $292M of sales.Annual report, filed Mar 2, 2026"We currently own 175 patents issued globally, including composition of matter patents covering our ready-to-use glucagon formulation that expire in 2036." (10-K for fiscal 2025)SEC filing · Mar 2, 2026
  • Where it stands3 findingsFor Pro members3 findings on where XERS stands: its cash, debt, and share count, for Pro members
  • What changed in its filings3 findings"On July 20, 2026, the United States District Court for the District of New Jersey entered an order consolidating for all pretrial purposes the actions against Novitium filed on June 4, 2026 and July 13, 2026 into the Consolidated Action." (10-Q for the quarter to Jun 30, 2026)SEC filing · Aug 6, 2026A new heading in its "Risk Factors" this year: "Federal legislative and regulatory efforts to implement reference pricing or most-favored-nation pricing models could impact our product revenues and materially harm our business." (10-K for fiscal 2025; not in fiscal 2024's)SEC filing · Mar 2, 2026, against the one of Mar 6, 2025
  • Who holds and trades it2 findingsFor Pro members2 findings on who holds and trades XERS, for Pro members
  • Against its closest peers1 peerShare count against a year before: XERS +8.4%, RCUS +19%.

9 more findings on XERS, each with its source, for Pro members.

XERS share count over time

Shares: 8.4% more than a year ago (to Jun 30).

Shares of XERS outstanding, as filed
Shares
outstanding
As
of
182.3MJul 31, 2026
172.6MApr 30, 2026
172.4MFeb 27, 2026
165.9MOct 31, 2025
Offerings, shelves, and splits of XERS, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3)Mar 6, 2025

XERS's officers and directors

Officers and directors with a Form 4 in the last 12 months.

5 more officers and directors file at XERS.

See insider trades by person

Which ETFs hold XERS?

In ETFs: XERS is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Xeris Biopharma Holdings

Xeris Biopharma Holdings Inc is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for people with chronic endocrine and neurological diseases in the United States. It offers Recorlev for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome; Gvoke for the treatment of severe hypoglycemia; and Keveyis for the treatment of Primary Periodic Paralysis (PPP). Additionally, the company is advancing its Phase 3-ready pipeline product, XP-8121, a once-weekly subcutaneous injection of levothyroxine, which leverages its proprietary technology, XeriSol.

435 employeesChicago, ILxerispharma.com

What Xeris Biopharma Holdings says it competes with

“Our industry is characterized by intense competition and a strong emphasis on proprietary products.”

From its annual report, SEC filing · Mar 2, 2026

Here is what Pro members see.

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  • What would move XERS's score: 3 things
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See XERS's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 9, 2026: XERS's Quality Score is 22 (Exceptional), #1 of 281 in Biotech.

What does XERS's Quality Score say?

XERS scores 22 today, which Breakaway calls Exceptional. It is #1 of 281 in Biotech by Quality Score, with 9 of 14 chart checks firing. Up 50% from Nov 2 to Nov 6 while the S&P 500 fell 2%. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is XERS's Quality Score?

XERS scores 22 today, which Breakaway calls Exceptional (20 or more). That is #1 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind XERS's 22.

When does XERS report earnings?

Expected to report Thu Mar 4, before the open, a date Breakaway expects from the company's usual timing; the company has not confirmed it. XERS closed higher after 2 of its last 4 reports. Past behavior, not a forecast.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

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What's next for Xeris Biopharma Holdings: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

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