Taysha Gene Therapies (TSHA) stock

Market cap $1.5B

$4.63
-2.32%

Market closed. Prices as of Friday's close.

Quality Score
-6
Poor
In its industry
#267of 300

TSHA's Quality Score fell 1 point on Fri, Oct 2, to -6.

Next1H 2027“…Food and Drug Administration (FDA) and is on track to report topline data and regulatory feedback in 1H 2027…”Trial data · 8-K, Aug 11

Follow TSHA's trial news. Pro members can get an alert when Taysha Gene Therapies files news, and see its trials, share raises, and its CEO's filings.

Get an optional alert when TSHA files news on its trialsSee it live, free until tomorrow morning. No account. No card. Then keep going with a free account.

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What's next for TSHA, and how long its cash lasts

From Taysha Gene Therapies’s SEC filings and ClinicalTrials.gov: the company’s own words, the registry’s dates, and arithmetic, not a forecast. Companies often miss their own dates.

Next step the company has named

1H 2027“…interim analysis and next steps in the BLA submission pathway with the U.S. Food and Drug Administration (FDA) and is on track to report topline data and regulatory feedback in 1H 2027.”Trial data · 8-K, Aug 11

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
ASPIREPhase 3 · Active · 4 people · main data estimated Jun 2031 · NCT07480564

2 more trials, 1 more milestone and 30 filings, for Pro members.

Cash runway

The company says its cash lasts into 2H 2028 (8-K, Aug 11).

That is the company's own estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Nov 4, 2025)
  • At-the-market share sales program (S-3ASR, filed Nov 4, 2025)

A shelf lets a company sell shares later; an at-the-market program sells them into the market over time. Neither is a sale by itself.

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

An officer, Sukumar Nagendran, sold 200,000 shares on Jul 10, under a planned sale. 6 more insider trades this year.

From their own Form 4 filings: buys and sales in the market, not awards or shares withheld for tax.

For Pro members: every trade, and Sean Nolan’s 3 filings and quotes.

Get an optional alert when TSHA files news on its trialsSee it live, free until tomorrow morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their own filings, soonest first and small companies first.

DateStockDrug

8 more FDA dates and 114 trial data dates in the next 60 days. Pro members see every one, with the cash against its date and an optional alert before it. Get in free →

Why it's down

Down 27% in 3 months, 18% under its 50-day average.

Down more than its industry: the 299 other stocks in it fell a median 14% over the same 3 months.

−2Growth sales down 32% on the year, operating margin down 1631.5 points

5 more things pulling TSHA's score down, for Pro members

What's next

Wed Oct 14: 55th Child Neurology Society (CNS)…Industry event · date confirmed.

Expected to report Wed Nov 4, after the close

After its last 4 reports it closed -1.3% on average, higher 2 of 4 times.

What would turn TSHA's score around: 9 things, for Pro members

Alert me when TSHA's Quality Score turns up

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TSHA has 1 of 14 checks firing

One per group is shown here.

Trend1 of 5 shown

Averages stacked in order, price near its high.

Volume1 of 3 shown

Heavy volume on the run, quiet volume at rest.

Tight range1 of 3 shown

The daily range is tight against its own recent history.

Buying1 of 3 shown

Closes near the high, and buyers step in on dips.

The other 10 checks on TSHA, and all 14 on every stock.Get in free →

Also on the chart

Not scored

Shown for reference. None of these counts toward the Quality Score: in our tests on 20 years of daily prices, none of them improved it.

  • RSI 1432.9

    Above 30, below 50.

  • MACD (12, 26, 9)Below signal

    Crossed below its signal line today.

  • The price is 17.6% below it.

  • The price is 15.2% below it. The 50-day is above the 200-day, since Jun 2, 2025.

  • ADX 1419.1

    Under 25, with +DI below -DI.

  • Support$4.43

    Swing low from Oct 17, 2025, 4.3% below the price.

  • Swing high from Mar 9, 3.0% above the price.

  • The bands run from $4.56 to $5.52.

  • Volume0.8x

    Against its 20-day average, for the time of day.

How TSHA ranks in Biotech

TSHA is #267 of 300 by Quality Score. The top three are shown with their scores, and more by name.

More in Biotech, on the Healthcare page

When does TSHA report earnings, and what happens after?

Expected to report Wed Nov 4, after the close (in 30 days). Not yet confirmed by the company.

ReportedGapReaction5 sessions
Aug 11, 2026After close-8.2%-4.1%-7.3%
May 6, 2026Before open-4.8%+0.6%-1.3%
Mar 19, 2026Before open+2.3%+2.5%+2.9%
Nov 4, 2025Before open-3.8%-4.3%-12.8%

The gap is the next open against the close before the report; the reaction is where that session closed. TSHA closed higher after 2 of its last 4. Past behavior, not a forecast.

Report dates and past reactions come from sessions that have already closed, so none of these figures move.

About Taysha Gene Therapies

Taysha Gene Therapies Inc is a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. The company's clinical program TSHA-102 is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. The Company views its operations and manages its business as a single operating segment, the gene therapy segment, which is the business of developing AAV-based gene therapies for the treatment of rare monogenic diseases of the central nervous system.

99 employeesDallas, TXtayshagtx.com

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