Palvella Therapeutics (PVLA) stock

Market cap $1.9B

$128.00
-3.15%

Market closed. Prices as of today's close.

Quality Score
1
Below Average
In its industry
#117of 300

PVLA's Quality Score fell 6 points on Tue, Oct 6, to 1. Its daily swings widened (4 chart checks stopped). 1 more reason, for Pro members.

Next2H 2026“…malformations submitted to FDA, with completion of the NDA submission on track for the second half of 2026”Filing with regulators · 8-K, Aug 4

Follow PVLA's trial news. Pro members can get an alert when Palvella Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an optional alert when PVLA files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Holding it back

A $42M loss.

2 more reasons behind PVLA's 1, for Pro members

What's next for PVLA, and how long its cash lasts

From Palvella Therapeutics’s SEC filings and ClinicalTrials.gov: the company’s own words, the registry’s dates, and arithmetic, not a forecast. Companies often miss their own dates.

Next step the company has named

2H 2026“First module of the rolling NDA for QTORIN™ rapamycin for microcystic lymphatic malformations submitted to FDA, with completion of the NDA submission on track for the second half of 2026”Filing with regulators · 8-K, Aug 4

What it means: a filing asks regulators to approve a drug for sale. Once it is complete and accepted, the FDA sets a decision date, and we show it here.

A trial underway
LOTUPhase 2 · Recruiting · 15 people · main data estimated Aug 2027 · NCT07552077

3 more trials, 5 more milestones and 39 filings, for Pro members.

Cash runway

The company says its cash lasts into 2H 2027 (8-K, Jan 29).

That is the company's own estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3, filed Jan 2, 2026)
  • At-the-market share sales program (S-3, filed Jan 2, 2026)

A shelf lets a company sell shares later; an at-the-market program sells them into the market over time. Neither is a sale by itself.

For Pro members: 2 raises and their amounts, and the share count against a year ago.

Insiders

Chief Operating Officer Kathleen Goin sold 4,302 shares on Sep 16, under a planned sale. 13 more insider trades this year.

From their own Form 4 filings: buys and sales in the market, not awards or shares withheld for tax.

For Pro members: every trade, and Wes Kaupinen’s 13 filings and quotes.

Get an optional alert when PVLA files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their own filings, soonest first and small companies first.

DateStockDrug

8 more FDA dates and 113 trial data dates in the next 60 days. Pro members see every one, with the cash against its date and an optional alert before it. Get in free →

Why PVLA beats the market

Palvella Therapeutics returned +95% over the past year to the S&P 500's +17%; its 5 peers' median returned +99%.

Its 5 peers' median return over the past year was +99%, from +12% (Mirum Pharmaceuticals) to +121% (Travere Therapeutics).

Sources: Price history, Oct 5, 2026

1 more driver, the timeline, and the peer table, for Pro members

Why PVLA scores 1

Below AverageTransition, 0 of 14 checks firingWhat the Quality Score means

Poor is below 0. Average starts at 6, Above Average at 11, Excellent at 15, and Exceptional at 20.

Well below its own recent run. PVLA scores 1 today, against a median of 10 over its last 20 recorded sessions.

  • +2Long-term trend above a rising 200-⁠day average
  • −1Profit Lost $41.7M in the year to Dec 31, 2025, more than the $17.4M lost the year before, from the SEC filingRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Persistence adds

No effect today: Chart checks, Run-up, Size, Growth, Dilution, Cash flow, News, and Insider trades.

What every line is worth, and the reason behind it, on PVLA and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 8:17 PM ET, at least 15 minutes behind. How we rank stocks.

What's next

Expected to report Wed Nov 11, before the open

After its last 4 reports it closed +1.1% on average, higher 2 of 4 times.

What would turn PVLA's score around: 6 things, for Pro members

Alert me when PVLA's Quality Score turns up

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Nothing is firing on PVLA right now

One per group is shown here.

Trend1 of 5 shown

Averages stacked in order, price near its high.

Volume1 of 3 shown

Heavy volume on the run, quiet volume at rest.

Tight range1 of 3 shown

The daily range is tight against its own recent history.

Buying1 of 3 shown

Closes near the high, and buyers step in on dips.

The other 10 checks on PVLA, and all 14 on every stock.Get in free →

Also on the chart

Not scored

Shown for reference. None of these counts toward the Quality Score: in our tests on 20 years of daily prices, none of them improved it.

How PVLA ranks in Biotech

PVLA is #117 of 300 by Quality Score. The top three are shown with their scores, and more by name.

More in Biotech, on the Healthcare page

When does PVLA report earnings, and what happens after?

Expected to report Wed Nov 11, before the open (in 36 days). Not yet confirmed by the company.

ReportedGapReaction5 sessions
Aug 4, 2026Before open-3.9%+8.0%+8.1%
May 7, 2026Before open-0.9%-13.0%-7.4%
Mar 31, 2026Before open+4.5%+12.6%+8.5%
Nov 10, 2025After close-5.2%-3.0%+1.7%

The gap is the next open against the close before the report; the reaction is where that session closed. PVLA closed higher after 2 of its last 4. Past behavior, not a forecast.

Report dates and past reactions come from sessions that have already closed, so none of these figures move.

Who is trading PVLA

PVLA insider trades

One insider sold $49K across 1 filing in the last 6 months. No open-⁠market buys on record. The newest:

SellChristopher P. Kiritsy$49KDirectorat $157.00 on Sep 2, filed Sep 4

An insider has two business days to file a Form 4, so the trade is already days old when it becomes public. Shown as filed, with no delay.

PVLA's officers and directors

Officers and directors with a Form 4 here in the last 3 months. Open one for their trades at every company.

See insider trades by person

About Palvella Therapeutics

Palvella Therapeutics Inc is a clinical-stage biopharmaceutical company whose vision is to become the rare disease biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare skin diseases and vascular malformations for which there are no FDA-approved therapies. Its product candidate, QTORIN 3.9% rapamycin anhydrous gel, is currently in clinical development for microcystic lymphatic malformations and cutaneous venous malformations. It operates in single segment.

29 employeesWayne, PApalvellatx.com

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BreakawaySep 4Christopher P. Kiritsy sold PVLA$49K at $157.00, filed Sep 4

What a filing on PVLA would have sent. Alerts are optional.

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Straight Answers

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