Vaxcyte (PCVX) logo

Vaxcyte (PCVX) stock

Bacterial vaccines , market cap $9.8B

$64.67
+1.22%

As of 9:33 AM ET, delayed 15+ min · Live for Pro members

Quality Score
2
Below Average
In its industry
#112of 281
Checks firing
4of 14
Trending up
From 52-week high
-28.7%
under its best in a year

PCVX's Quality Score rose 1 point on Mon, Nov 9, to 2.

Follow PCVX's trial news. Pro members can get an alert when Vaxcyte files news, and see its trials, share raises, and its CEO's filings.

Get an alert when PCVX files news on its trialsSee it live, free for 24 hours. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Next1H 2027“…dose of the ongoing Phase 2 study, either sequentially or together, by the end of the first half of 2027…”Trial data · SEC filing · Nov 4

Why PCVX fell on Nov 5

Down 5.7% on Nov 5, a down day for the market: the S&P 500 fell 4%, 86% of stocks fell, and biotech stocks a median 6.3%.

  • Its Nov 4 results: net loss widened to $297.1M, from $212.8M a year before. It fell 6% on Nov 5.

Sources: Price history, Nov 5, 2026; Company release, Nov 4, 2026

1 more reason, free with an account →1 more reason why PCVX fell on Nov 5, from its filings, with the timeline and its peers, for Pro members.

Key facts on PCVX

Key facts on PCVX
Holding it backA $1.1B loss wider than $547M a year earlier
Latest filing8-K, Nov 4 Reported its quarterly results
1 more reason behind PCVX's 2, free with an account →2 more reasons behind PCVX's 2, for Pro members.

PCVX in the news

Thu Nov 5Form 8K Vaxcyte Inc For: 4 November By Investing.com investing.com canada and 1 more · yesterday 4:24 PM ET PCVX closed −5.7% that day.

Big story

Mon Oct 5: Trial

Vaxcyte Reports Positive Topline Data from OPUS-1, the Pivotal Adult Phase 3 Trial of VAX-31, the Company's 31-Valent Pneumococcal Conjugate Vaccine Candidate

PCVX closed +30.7% that day on 12.5x normal volume.

Reported by yahoo finance · covered by 3 outlets

Get an alert on PCVX's next big story →

Outlet counts from the GDELT Project. The move is what PCVX did that session, not a claim about why.

PCVX catalysts

Coming up

After its last 4 reports it closed -1.9% on average, higher 2 of 4 times.

11 past catalysts since 2022, with sizes and sources, for Pro members.

What's next for PCVX, and how long its cash lasts

Next step the company has named

1H 2027“…expect to announce topline data from the primary immunization series and booster dose of the ongoing Phase 2 study, either sequentially or together, by the end of the first half of 2027.”Trial data · SEC filing · Nov 4

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal VaccinationPhase 3 · Active · 752 people · main data estimated Mar 2027 · NCT07425392

3 more trials, 1 more milestone and 33 filings, for Pro members.

Cash runway

The company says its cash lasts into Mid-2028 (8-K, Nov 4, 2025).

That is the company's estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed May 24, 2024)
  • At-the-market share sales program (424B5, filed Feb 24, 2026)

For Pro members: 6 raises and their amounts, and the share count against a year ago.

Insiders

SVP, Finance & CAO Elvia Cowan sold 3,000 shares on Nov 2, under a planned sale. 22 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Grant Pickering’s 26 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why PCVX scores 2

Below Averagefor quality, not price, 4 of 14 chart checks firingWhat the Quality Score means

  • +4Chart checks 4 of 14 firing right now, one point each
  • +1Long-term trend above a rising 200-⁠day average, down over two years
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Run-up, Size, Growth, Dilution, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on PCVX and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 9:33 AM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How PCVX ranks in Biotech

PCVX is #112 of 281 by Quality Score.

How PCVX ranks in Biotech
RankStockQuality Score
112Vaxcyte (PCVX) logoPCVXVaxcyte2

Share count against a year before: PCVX +6.2%, IMVT +20%, RLAY +18%, MRNA +2.8%.

More in Biotech

When does PCVX report earnings, and what happens after?

Expected to report Tue Feb 23, after the close (in 106 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What PCVX reported on Nov 4, 2026

The quarter

A loss of $1.99 a share, from $1.56.

“The increase was due primarily to higher development and product manufacturing costs associated with the Company's PCV programs, including manufacturing activities to support the potential future commercial launches and clinical trial expenses primarily related to the VAX-31 OPUS Phase 3 trials, as well as higher personnel expenses related to the growth in the number of R&D employees.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

PCVX's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The increase was due primarily to higher personnel expenses related to the growth in the number of G&A employees and professional and consulting services.”

From its results filing (SEC filing · Nov 4)

The numbers

Market value
$9.8B
today
Free cash flow
-$894M
last 12 months

No analyst estimates on Breakaway: every figure here is filed.

The whole report on PCVX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-9.8%+5.3%-5.7%
May 6Aug 5Nov 4
ReportedGapReaction5
days
Nov 4, 2026After close+0.3%-5.7%not yet
Aug 5, 2026After close-1.3%+5.3%+6.7%
May 6, 2026After close-3.7%-9.8%-5.0%

PCVX closed higher after 2 of its last 4 reports.

All 4 reports, and PCVX's Quality Score going into each

PCVX has 4 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on PCVX, and all 14 on every stock.Get in free →

PCVX RSI today: 53.9, above its 50-day and 200-day averages

Not scored

RSI 53.9, MACD above signal, above both averages. Not scored.

The deep dive on PCVX

9 more findings on PCVX, each with its source, for Pro members.

PCVX share count over time

Shares: 6.2% more than a year ago (to Jun 30).

Shares of PCVX outstanding, as filed
Shares
outstanding
As
of
148.8MAug 3, 2026
144.4MMay 4, 2026
143.9MFeb 20, 2026
130.9MOct 31, 2025
Offerings, shelves, and splits of PCVX, from its filings
From its
filings
Filed
Sold $500M of convertible notes, about 5% of its market valueOct 8, 2026
Sold $75M of convertible notesOct 8, 2026
Set up an at-the-market program for up to $500M of shares, about 5% of its market valueFeb 24, 2026
Raised $550M in a sale of shares, about 6% of its market valueJan 30, 2026

3 more offerings on file, for Pro members.

PCVX insider trades

One insider sold $376K across 6 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellJim Wassil$84KEVP, Chief Scientific Ofc, COOat $61.16 on Sep 4, filed Sep 9

All 6 insider filings on PCVX from the last six months, for Pro members.

All PCVX insider trades

PCVX trades by Congress and the executive branch

3 trades disclosed in the last six months. The newest:

BuyGilbert Cisneros$1K to $15KHousetraded Jul 16, disclosed Sep 4(50 days later)
All 3 trades on PCVX disclosed by Congress and the executive branch, for Pro members.Get in free →

See what Congress is buying across the market

PCVX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

6 more officers and directors file at PCVX.

See insider trades by person

Which ETFs hold PCVX?

In ETFs: PCVX is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Vaxcyte

Vaxcyte Inc is a clinical-stage vaccine company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. It uses the XpressCF cell-free protein synthesis platform to develop potentially superior and novel conjugate and protein vaccine candidates for adult and pediatric indications. The company's product pipeline includes: VAX-31, VAX-24, and VAX-XL PCV vaccine candidates; VAX-A1, a Novel Group A Strep Vaccine; and VAX-GI, a Novel Shigella Vaccine, among others, in their different stages of development.

507 employeesSan Carlos, CAvaxcyte.com

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  • What would turn PCVX's score around: 7 things
  • 10 more filings explained, a plain line each
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BreakawaySep 4Gilbert Cisneros bought PCVX$1K to $15K, disclosed Sep 4

Alerts are optional.

See PCVX's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 9, 2026: PCVX's Quality Score is 2 (Below Average), #112 of 281 in Biotech. Insiders sold $376K in the last 6 months (Form 4).

What does PCVX's Quality Score say?

PCVX scores 2 today, which Breakaway calls Below Average. It is #112 of 281 in Biotech by Quality Score, with 4 of 14 chart checks firing. Down 5.7% on Nov 5, a down day for the market: the S&P 500 fell 4%, 86% of stocks fell, and biotech stocks a median 6.3%. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is PCVX's Quality Score?

PCVX scores 2 today, which Breakaway calls Below Average (0 to 5). That is #112 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind PCVX's 2.

Are insiders buying PCVX?

One insider sold $376K across 6 filings in the last 6 months. No open-⁠market buys on record. The newest is Jim Wassil, EVP, Chief Scientific Ofc, COO, who sold $84K on Sep 4. Every filing, with the scored weight, for Pro members.

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What's next for Vaxcyte: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

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