Madrigal Pharmaceuticals (MDGL) stock

Market cap $12B

$499.40
-0.06%

Market closed. Prices as of today's close.

Quality Score
4
Below Average
In its industry
#89of 300
Cash$839M in cash. One of the last four quarters brought cash in while the others used it.On Jun 30 · the company says “into 2045”

Follow MDGL's trial news. Pro members can get an alert when Madrigal Pharmaceuticals files news, and see its trials, share raises, and its CEO's filings.

Get an optional alert when MDGL files news on its trialsFree for 24 hours. No account needed.
Cash$839M in cash. One of the last four quarters brought cash in while the others used it.On Jun 30 · the company says “into 2045”
Pipeline and cash

What's next for MDGL, and how long its cash lasts

From Madrigal Pharmaceuticals’s SEC filings and ClinicalTrials.gov: the company’s own words, the registry’s dates, and arithmetic, not a forecast. Companies often miss their own dates.

Its trials

A trial underway
Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)Phase 3 · Active · 845 people · main data estimated Dec 2026 · NCT05500222

6 more trials, 31 filings, for Pro members.

Cash runway Jun 30 balance sheet

$839M in cash

One of the last four quarters brought cash in while the others used it, so an average says little about the next.

What it means: a runway is counted only when each of the last four quarters used cash. The company's own estimate is “into 2045” (8-K, May 6).

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed May 7, 2024)
  • At-the-market share sales program (S-3ASR, filed May 7, 2024)

A shelf lets a company sell shares later; an at-the-market program sells them into the market over time. Neither is a sale by itself.

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

CEO William John Sibold sold 11,583 shares on Sep 11, under a planned sale. 20 more insider trades this year.

From their own Form 4 filings: buys and sales in the market, not awards or shares withheld for tax.

For Pro members: every trade, and William Sibold’s 10 filings and quotes.

See every upcoming FDA date →

Biotech dates

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their own filings, soonest first and small companies first.

DateStockDrug

8 more FDA dates and 114 trial data dates in the next 60 days. Pro members see every one, with the cash against its date and an optional alert before it. Get in free →

Quality Score

Why MDGL scores 4

Below AverageTransition, 1 of 14 checks firingWhat the Quality Score means

Poor is below 0. Average starts at 6, Above Average at 11, Excellent at 15, and Exceptional at 20.

Well below its own recent run. MDGL scores 4 today, against a median of 8.5 over its last 20 recorded sessions.

  • −1Profit Lost $325M over the last four quarters, more than the $282M lost a year earlier, from the SEC filingsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • +3Growth sales up 149% on the year, operating margin up 35.0 pointsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Chart checks adds
  • Long-term trend adds
  • Size adds
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Run-up, Dilution, Volatility, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on MDGL and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 8:40 PM ET, at least 15 minutes behind. How we rank stocks.

What's next

Expected to report Wed Nov 4, before the open

After its last 4 reports it closed -1.4% on average, higher 2 of 4 times.

What would turn MDGL's score around: 6 things, for Pro members

Alert me when MDGL's Quality Score turns up

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Pro

Here is what Pro members see.

Every stock has a live page like this, MDGL included: the price in real time, the full chart, all 14 checks, and every line of its score.

AMD's page for Pro members on a phone, recorded live: the price changes as it trades, beside its Quality Score and its rank, with the bid and ask under it and a year of candles below
The same page for Pro members, on AMDThe live price and the full chart, with the Quality Score drawn under it and the line that drives it.
The Score tab on a phone: how AMD's Quality Score adds up from price action, the company, and signals, its rank, and the chart checks by group, trend, volume, tight range, and buying
Every line of the scoreWhat each part adds, and all 14 checks by group, on MDGL and every other stock.
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The 14 checks

MDGL has 1 of 14 checks firing

One per group is shown here.

Trend1 of 5 shown

Averages stacked in order, price near its high.

Volume1 of 3 shown

Heavy volume on the run, quiet volume at rest.

Tight range1 of 3 shown

The daily range is tight against its own recent history.

Buying1 of 3 shown

Closes near the high, and buyers step in on dips.

The other 10 checks on MDGL, and all 14 on every stock.Get in free →

Also on the chart

Not scored

Shown for reference. None of these counts toward the Quality Score: in our tests on 20 years of daily prices, none of them improved it.

  • RSI 1436.5

    Above 30, below 50.

  • MACD (12, 26, 9)Below signal

    Crossed below its signal line 13 sessions ago.

  • The price is 4.6% below it.

  • The price is 2.2% below it. The 50-day is above the 200-day, since Aug 21, 2025.

  • ADX 1418.3

    Under 25, with +DI below -DI.

  • Support$499.34

    Swing low from May 20, 0.0% below the price.

  • Resistance$499.55

    Swing high from Feb 10, 0.0% above the price.

  • The bands run from $495.80 to $550.30.

  • Volume1.3x

    Against its 20-day average, for the time of day.

Its industry

How MDGL ranks in Biotech

MDGL is #89 of 300 by Quality Score. The top three are shown with their scores, and more by name.

More in Biotech, on the Healthcare page

Earnings

When does MDGL report earnings, and what happens after?

Expected to report Wed Nov 4, before the open (in 33 days). Not yet confirmed by the company.

ReportedGapReaction5 sessions
Jul 30, 2026Before open-7.6%-9.8%-6.0%
May 6, 2026Before open+5.7%+7.4%+1.6%
Feb 19, 2026Before open-8.0%-11.1%-11.5%
Nov 4, 2025Before open-1.5%+7.8%+20.3%

The gap is the next open against the close before the report; the reaction is where that session closed. MDGL closed higher after 2 of its last 4. Past behavior, not a forecast.

Report dates and past reactions come from sessions that have already closed, so none of these figures move.

Filings

Who is trading MDGL

MDGL insider trades

2 insiders sold $1.7M across 11 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellShannon T Kelley$342KGeneral Counselat $514.97 on Aug 17, filed Aug 20
All 11 insider filings on MDGL from the last six months, for Pro members.Get in free →

An insider has two business days to file a Form 4, so the trade is already days old when it becomes public. Shown as filed, with no delay.

The company

About Madrigal Pharmaceuticals

Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.

915 employeesWest Conshohocken, PAmadrigalpharma.com

Pro

Every line of the score, on every stock.

  • Real-time prices, no delay
  • Every line of MDGL's score, with the points and the reason
  • All 14 checks on MDGL and on all 3,243 stocks
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  • Every filing, and optional alerts on MDGL
BreakawayAug 20Shannon T Kelley sold MDGL$342K at $514.97, filed Aug 20

What a filing on MDGL would have sent. Alerts are optional.

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Questions

Straight Answers.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, trial included, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

Where does the data come from?

Daily bars, quotes, reference data, headlines, and short interest come from Massive, formerly Polygon, a licensed market data vendor. The age of the quotes is shown at the top of every page. Insider trades, notable holders and profits come straight from the SEC. That means Form 4 filings, 13F filings and XBRL financial data on EDGAR. Government filings come from the public STOCK Act and Office of Government Ethics disclosures. The market-wide headlines on the market line also come from the public headline feeds CNBC, MarketWatch and Yahoo Finance publish, shown as the headline, the source and a link to the article. Splits, dividends, and the financial statements on each ticker page come from the vendor's reference data. The 8-K filings on EDGAR are read for the items that move a price. Five years of history is loaded for every stock. So the 200-day and 52-week checks rest on real history. Options flow is not part of the product.

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Is this investment advice?

No. It is a screening tool that scores stocks on the chart, the company's own results, and the news and filings. It does not know your situation and it is not a recommendation to buy or sell anything. Please do your own research.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes. Filings are shown as filed, because a disclosure is already days or weeks old when it becomes public. Earnings dates and past reactions are settled sessions.