MBX Biosciences (MBX) logo

MBX Biosciences (MBX) stock

$56.33
+4.20%

Peptide medicines, worth $2.3BGLP-1 and obesity drugs

As of Tuesday's close · Live for Pro members at the open

Quality Score
4
Below Average
In its industry
#88of 281
Checks firing
5of 14
Choppy
From 52-week high
-22.5%
under its best in a year

MBX's Quality Score rose 2 points on Tue, Nov 10, to 4. Its week-by-week trend turned up (3 chart checks started).

Follow MBX's trial news. Pro members can get an alert when MBX Biosciences files news, and see its trials, share raises, and its CEO's filings.

Get an alert when MBX files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ4 2026“…MBX 4291, a GLP-1/GIP co-agonist prodrug for obesity designed for once-monthly dosing, on track for Q4 2026”Trial data · SEC filing · Nov 9

Key facts on MBX

Key facts on MBX
Holding it back42.0% more shares than a year ago
Latest filing8-K, Nov 9 Reported its quarterly results
1 more reason behind MBX's 4, free with an account →4 more reasons behind MBX's 4, for Pro members.

MBX in the news

ReportLast night: a loss of $1.29 a share. Past reports ›

What's next

Tue Nov 10: Guggenheim 3rd Annual Global…Investor conference · date confirmed.

2 more dates ahead: conferences, for Pro members.

MBX catalysts

Coming up

After its last 4 reports it closed +4.6% on average, higher 2 of 4 times.

What's next for MBX, and how long its cash lasts

Next step the company has named

Q4 2026“12-week MAD (Part C, Cohort 1) data for MBX 4291, a GLP-1/GIP co-agonist prodrug for obesity designed for once-monthly dosing, on track for Q4 2026”Trial data · SEC filing · Nov 9

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Canvuparatide Compared With Placebo in Adult Patients With HypoparathyroidismPhase 3 · Recruiting · 160 people · main data estimated Jan 2028 · NCT07699471

2 more trials, 29 filings, for Pro members.

Cash runway

The company says its cash lasts into 2029 (8-K, Nov 9).

That is the company's estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Mar 12, 2026)
  • At-the-market share sales program (S-3ASR, filed Mar 12, 2026)

For Pro members: 2 raises and their amounts, and the share count against a year ago.

Insiders

Chief Medical Officer Salomon Azoulay sold 373 shares on Nov 4. 5 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Steven Hoerter’s 14 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why MBX scores 4

Below Averagefor quality, not price, 5 of 14 chart checks firingWhat the Quality Score means

  • +5Chart checks 5 of 14 firing right now, one point each
  • +2Long-term trend above a rising 200-⁠day average
  • Run-up adds
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Dilution subtractsNew shares over the year: -1 at 10% more, -2 at 25% more.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Size, Growth, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on MBX and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:29 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How MBX ranks in Biotech

MBX is #88 of 281 by Quality Score.

How MBX ranks in Biotech
RankStockQuality Score
88MBX Biosciences (MBX) logoMBXMBX Biosciences4

Share count against a year before: MBX +42%, VKTX +5.1%, WVE +22%, GPCR +25%.

More in Biotech

When does MBX report earnings, and what happens after?

Expected to report Thu Mar 18, after the close (in 128 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What MBX reported on Nov 9, 2026

The quarter

A loss of $1.29 a share, from $0.63.

“The increase of $12.7 million was driven by an increase in start-up costs related to the canvuparatide Phase 3 clinical trial which was initiated in the third quarter of 2026, ongoing conduct of the canvuparatide Phase 2 open-label extension clinical trial, ongoing conduct of the MBX 4291 Phase 1 clinical trial and timing of preclinical and IND-enabling activities related to MBX 5765 and MBX 6180.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

MBX's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The increase of $29.6 million was driven by higher personnel-related costs, including $20.8 million of stock-based compensation expense related to the modification of awards for the Company’s former chief executive officer, and other higher personnel-related costs resulting from continued expansion of both the Company’s executive leadership team and general infrastructure to support growth in the Company’s operations.”

From its results filing (SEC filing · Nov 9)

1 more sentence, for Pro members.

The numbers

Market value
$2.3B
today
Free cash flow
-$99.3M
last 12 months

1 more figure, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on MBX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+18.0%-0.6%+4.2%
May 7Aug 6Nov 9
ReportedGapReaction5
days
Nov 9, 2026After close-4.7%+4.2%not yet
Aug 6, 2026Before open-1.9%-0.6%-0.8%
May 7, 2026No time given+0.7%+18.0%+1.9%

MBX closed higher after 2 of its last 4 reports.

All 4 reports, and MBX's Quality Score going into each

MBX has 5 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on MBX, and all 14 on every stock.Get in free →

MBX RSI today: 55.0, above its 50-day and 200-day averages

Not scored

RSI 55.0, MACD above signal, above both averages. Not scored.

The deep dive on MBX

6 more findings on MBX, each with its source, for Pro members.

MBX share count over time

Shares: 42.0% more than a year ago (to Sep 30).

Shares of MBX outstanding, as filed
Shares
outstanding
As
of
49.7MNov 5, 2026
48.2MAug 3, 2026
47.6MMay 4, 2026
47.5MMar 6, 2026
Offerings, shelves, and splits of MBX, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Mar 12, 2026
Registered shares for a later sale (S-3)Nov 6, 2025
Raised $199.9M in a sale of shares, about 9% of its market valueSep 25, 2025
Registered shares for sale (S-1)Sep 22, 2025

MBX insider trades

One insider sold $44K across 2 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellSalomon Azoulay$20KChief Medical Officerat $53.96 on Nov 4, filed Nov 5

MBX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold MBX?

In ETFs: MBX is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About MBX Biosciences

MBX Biosciences Inc is a clinical stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders. The company designed its proprietary Precision Endocrine Peptide, or PEP, platform to overcome the key limitations of unmodified and modified peptide therapies to improve clinical outcomes and simplify disease management for patients. Its PEPs are selectively engineered to have optimized pharmaceutical properties, including extended time-action profiles and consistent drug concentrations with low peak-to-trough concentration ratios, consistent exposure to target tissues, and less frequent dosing. Its product candidates include canvuparatide (MBX 2109), imapextide (MBX 1416), and MBX 4291.

63 employeesCarmel, INmbxbio.com

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    Who reports each day, and how each stock took its last four reports.

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  • What would turn MBX's score around: 7 things
  • 8 more filings explained, a plain line each
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BreakawayNov 5Salomon Azoulay sold MBX$20K at $53.96, filed Nov 5

Alerts are optional.

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Straight AnswersStraight Answers

As of Nov 10, 2026: MBX's Quality Score is 4 (Below Average), #88 of 281 in Biotech. Insiders sold $44K in the last 6 months (Form 4).

What does MBX's Quality Score say?

MBX scores 4 today, which Breakaway calls Below Average. It is #88 of 281 in Biotech by Quality Score, with 5 of 14 chart checks firing. Shares: 42.0% more than a year ago (to Sep 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is MBX's Quality Score?

MBX scores 4 today, which Breakaway calls Below Average (0 to 5). That is #88 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind MBX's 4.

Are insiders buying MBX?

One insider sold $44K across 2 filings in the last 6 months. No open-⁠market buys on record. The newest is Salomon Azoulay, Chief Medical Officer, who sold $20K on Nov 4. Every filing, with the scored weight, for Pro members.

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What's next for MBX Biosciences: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

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