Bicycle Therapeutics (BCYC) logo

Bicycle Therapeutics (BCYC) stock

Worth $244M

$3.69
-2.12%

As of 11:01 AM ET, delayed 15+ min · Live for Pro members

Quality Score
-3
Poor
In its industry
#202of 281
Checks firing
3of 14
Choppy
From 52-week high
-52.9%
under its best in a year

BCYC's Quality Score rose 1 point on Tue, Nov 10, to -3.

Follow BCYC's trial news. Pro members can get an alert when Bicycle Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an alert when BCYC files news on its trialsSee it live, free for 24 hours. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Why is BCYC down?

Down 94% over five years while the S&P 500 rose 72%.

“The decrease in collaboration revenue of $9.1 million was primarily due to the termination of our collaboration programs with Genentech and Novartis.”

Bicycle Therapeutics' Apr 30 release said

Sources: Price history, Nov 9, 2026; Company release, Apr 30, 2026

1 more reason, free with an account →2 more reasons why BCYC lags the market, from its filings, with the company's words, the timeline, and its peers, for Pro members.

Key facts on BCYC

Key facts on BCYC
Since its Nov 2021 highDown 94% a $66.8M loss → a $141.8M loss a year
Latest filing8-K, Oct 29 Reported its quarterly results
1 more reason behind BCYC's -3, free with an account →4 more reasons behind BCYC's -3, for Pro members.

BCYC in the news

Thu Nov 5State Bicycle expands affordable build options for 4130 Trail escape collective and 1 more · yesterday 9:02 AM ET BCYC closed −6.5% that day.

BCYC catalysts

Coming up

After its last 4 reports it closed +0.6% on average, higher 2 of 4 times.

What's next for BCYC, and how long its cash lasts

Its trials

A trial underway
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 ExpressionPhase 1/2 · Active · 288 people · main data estimated Dec 31, 2026 · NCT04180371

7 more trials, 33 filings, for Pro members.

Cash runway

The company says its cash lasts into 2030 (8-K, Oct 29).

That is the company's estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

No shelf registration or at-the-market program on file in the last three years.

For Pro members: the amounts, and the share count against a year ago.

Insiders

Chief Operating Officer Jennifer Scott Perry sold 356 shares on Oct 5, under a planned sale. 22 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Kevin Lee’s 9 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why BCYC scores -3

Poorfor quality, not price, 3 of 14 chart checks firingWhat the Quality Score means

  • +3Chart checks 3 of 14 firing right now, one point each
  • −3Long-term trend below a falling 200-⁠day average, down over one year, down over two years
  • Size subtracts
  • Growth addsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.
  • Insider trades subtracts

No effect today: Run-up, Profit, Dilution, Persistence, and News.

What every line is worth, and the reason behind it, on BCYC and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:01 AM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How BCYC ranks in Biotech

BCYC is #202 of 281 by Quality Score.

How BCYC ranks in Biotech
RankStockQuality Score
202Bicycle Therapeutics (BCYC) logoBCYCBicycle Therapeutics-3

More in Biotech

When does BCYC report earnings, and what happens after?

Expected to report Tue Mar 16, before the open (in 126 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What BCYC reported on Oct 29, 2026

The quarter

A loss of $0.15 a share, from $0.85.

“The decrease in cash and cash equivalents is primarily due to cash used in operations, including cash payments for clinical program activities.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

BCYC's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “Cash and cash equivalents of $469.9 million as of September 30, 2026, with expected cash runway into 2030”

From its results filing (SEC filing · Oct 29)

The numbers

Market value
$244M
today
Sales
$83.5M
up 195% on the year
Free cash flow
-$177M
last 12 months

2 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on BCYC: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-0.2%+3.9%-1.6%
Apr 30Jul 30Oct 29
ReportedGapReaction5
days
Oct 29, 2026Before open+1.0%-1.6%-4.1%
Jul 30, 2026Before open0.0%+3.9%+2.9%
Apr 30, 2026Before open-1.5%-0.2%+8.9%

BCYC closed higher after 2 of its last 4 reports.

All 4 reports, and BCYC's Quality Score going into each

BCYC sales and profit by year

Sales and profit by year

Sales grew in six of the last seven years, to $72.6M in 2025. It lost money in each of the eight years.

BCYC has 3 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on BCYC, and all 14 on every stock.Get in free →

BCYC RSI today: 50.0, below its 50-day and 200-day averages

Not scored

RSI 50.0, MACD above signal, below both averages. Not scored.

The deep dive on BCYC

7 more findings on BCYC, each with its source, for Pro members.

BCYC share count over time

Shares: 1.0% more than a year ago (to Sep 30).

Shares of BCYC outstanding, as filed
Shares
outstanding
As
of
30MMay 1, 2023
30MFeb 23, 2023
29.7MOct 31, 2022
29.7MAug 1, 2022
Offerings, shelves, and splits of BCYC, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3)Aug 8, 2025

BCYC insider trades

5 insiders sold $112K across 17 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellKevin Lee$21KChief Executive Officerat $3.47 on Oct 2, filed Oct 6

All 17 insider filings on BCYC from the last six months, for Pro members.

All BCYC insider trades

BCYC's officers and directors

Officers and directors with a Form 4 in the last 12 months.

7 more officers and directors file at BCYC.

See insider trades by person

About Bicycle Therapeutics

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops that stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical needs. The company's product candidate, BT1718, is a Bicycle Toxin Conjugate, or BTC. The company has two segments: the United Kingdom and the United States. It derives maximum revenue from United Kingdom.

288 employeesCambridgebicycletherapeutics.com

What Bicycle Therapeutics says it competes with

“The biotechnology and pharmaceutical industries are characterized by rapidly advancing technologies, intense competition and a strong emphasis on proprietary products.”

From its annual report, SEC filing · Mar 17, 2026

Here is what Pro members see.

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    Price action, the company, and signals, each with its points, on BCYC and every other stock.

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    Each date in the company's words, its cash against the date, and an optional alert before it.

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    Every CEO buy, biggest names first. Sort, filter, save the list, and set optional alerts.

  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

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Pro members see every line of every stock's score.

  • What would turn BCYC's score around: 7 things
  • 3 more filings explained, a plain line each
  • Real-⁠time prices, no delay
BreakawayOct 6Kevin Lee sold BCYC$21K at $3.47, filed Oct 6

Alerts are optional.

See BCYC's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: BCYC's Quality Score is -3 (Poor), #202 of 281 in Biotech. Insiders sold $112K in the last 6 months (Form 4).

What does BCYC's Quality Score say?

BCYC scores -3 today, which Breakaway calls Poor. It is #202 of 281 in Biotech by Quality Score, with 3 of 14 chart checks firing. Down 94% over five years while the S&P 500 rose 72%. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is BCYC's Quality Score?

BCYC scores -3 today, which Breakaway calls Poor (below zero). That is #202 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind BCYC's -3.

Are insiders buying BCYC?

5 insiders sold $112K across 17 filings in the last 6 months. No open-⁠market buys on record. The newest is Kevin Lee, Chief Executive Officer, who sold $21K on Oct 2. Every filing, with the scored weight, for Pro members.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

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Insider and Congress trades, the chart, and the financials, in one score.

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What's next for Bicycle Therapeutics: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

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