Vertex Pharmaceuticals (VRTX) logo

Vertex Pharmaceuticals (VRTX) stock

Drugs for diseases , market cap $138B

$547.89
-0.54%

As of Tuesday's close · Live for Pro members at the open

Quality Score
16
Excellent
In its industry
#17of 281
Checks firing
6of 14
Trending up
From 52-week high
-3.7%
under its best in a year

VRTX's Quality Score fell 1 point on Tue, Nov 10, to 16. It closed away from its high of the day (2 chart checks stopped).

Follow VRTX's trial news. Pro members can get an alert when Vertex Pharmaceuticals files news, and see its trials, share raises, and its CEO's filings.

Get an alert when VRTX files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextNov 30, 2026 · In 20 days“…IgAN is under priority review by the U.S. FDA, with an assigned PDUFA target action date of November 30, 2026…”FDA decision date · SEC filing · Nov 2

Why is VRTX down?

Down 4% on Nov 3 while the S&P 500 rose 0.3%.

  • Its Nov 2 results: diluted net income per share was $2.56, from $4.20 a year before. It fell 4% on Nov 3.

Sources: Price history, Nov 3, 2026; Company release, Nov 2, 2026

1 more reason, free with an account →2 more reasons why VRTX fell on Nov 3, from its filings, with the timeline and its peers, for Pro members.

Why VRTX still beats the market over five years

Up 188% over the five years to Nov 9 while the S&P 500 rose 72%; down 4% on Nov 3.

6 reasons, from its filings, with the timeline and its peers, for Pro members.

Key facts on VRTX

Key facts on VRTX
OutperformingUp 22% in 6 months vs the S&P's +2%
Latest filing10-Q, Nov 3 Filed its quarterly report (10-Q) for the quarter to Sep 30, 2026
1 more reason behind VRTX's 16, free with an account →4 more reasons behind VRTX's 16, for Pro members.

VRTX in the news

What's next

Mon Nov 16: UBS Global Biopharma Conference 2026Investor conference · date confirmed.

Expected to report Thu Feb 11, after the close

After its last 4 reports it closed +0.5% on average, higher 2 of 4 times.

2 more dates ahead: conferences, for Pro members.

VRTX catalysts

Coming up

6 more coming up and 36 past catalysts since 2018, with sizes and sources, for Pro members.

What's next for VRTX

Next step the company has named

Nov 30In 20 days“The BLA submission for accelerated approval of povetacicept in IgAN is under priority review by the U.S. FDA, with an assigned PDUFA target action date of November 30, 2026.”FDA decision date · SEC filing · Nov 2

What it means: the date by which the FDA has said it aims to decide on the company’s application. The FDA can decide earlier, or extend the date.

More on Povetacicept's FDA date

Lead program
Povetacicept · under FDA review
Another trial
Evaluation of the Long-term Safety and Effectiveness of Suzetrigine in Participants With Painful Diabetic Peripheral NeuropathyPhase 3 · Active · 455 people · main data estimated Jan 25, 2027 · NCT06696443

30 more trials, 1 with data due this year, 11 drugs past Phase 1 and 29 filings, for Pro members.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Feb 13, 2025)

For Pro members: the amounts, and the share count against a year ago.

Insiders

An officer, Ourania Tatsis, sold 1,500 shares on Jul 2, under a planned sale. 45 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Reshma Kewalramani’s 19 filings and quotes.

Get an alert before VRTX's FDA date

A free account. No card.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why VRTX scores 16

Excellentfor quality, not price, 6 of 14 chart checks firingWhat the Quality Score means

  • +6Chart checks 6 of 14 firing right now, one point each
  • +4Long-term trend above a rising 200-⁠day average, near its 52-⁠week high, at a multi-⁠year high
  • Size adds
  • Profit addsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Growth addsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Persistence adds
  • News adds

No effect today: Run-up, Dilution, Volatility, and Cash flow.

What every line is worth, and the reason behind it, on VRTX and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:29 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How VRTX ranks in Biotech

VRTX is #17 of 281 by Quality Score.

How VRTX ranks in Biotech
RankStockQuality Score
17Vertex Pharmaceuticals (VRTX) logoVRTXVertex Pharmaceuticals16

Net income over four quarters: VRTX $3.98B, MRK $2.45B.

More in Biotech

When does VRTX report earnings, and what happens after?

Expected to report Thu Feb 11, after the close (in 93 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What VRTX reported on Nov 2, 2026

The quarter

Sales of $3.4B, 12% more than a year ago; a profit of $2.56 a share, from $4.20.

“Total revenue increased 12% to $3.44 billion compared to the third quarter of 2025, primarily driven by the continued performance of cystic fibrosis (CF) therapies and growth from diversification into additional disease areas.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

Where the quarter's sales came from
LineQ3
2026
Q2
2026
Q3
2025
By product
Productup 12%$3.4B51%$3.3B51%$3.1B50%

Each quarter's sales and their share of its total. Figures as filed (SEC filing, Nov 3)

11 more lines, for Pro members.

The outlook

The outlook the company gave, by period
MeasureFigure
Full year 2026
Total revenue$13.15B to $13.25Braised

Figures as filed (SEC filing, Nov 2)

3 more outlook lines, for Pro members.

In the company's words

  • “The year-over-year decline is primarily due to expenses related to the Crinetics Pharmaceuticals acquisition.”

From its results filing (SEC filing · Nov 2)

The numbers

Market value
$138B
today
Sales
$13B
up 10.5% on the year
Free cash flow
$3.2B
last 12 months

Sales grew 14% a year over 5 years, fiscal 2020 to 2025.

Its share count fell 0.4% a year over 5 years.

5 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on VRTX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-1.3%+1.7%-4.0%
May 4Aug 3Nov 2
ReportedGapReaction5
days
Nov 2, 2026After close+1.0%-4.0%-0.4%
Aug 3, 2026After close+0.1%+1.7%+11.3%
May 4, 2026After close+0.5%-1.3%+1.2%

VRTX closed higher after 2 of its last 4 reports.

All 4 reports, and VRTX's Quality Score going into each

VRTX sales and profit by year

Sales and profit by year

Sales grew every year from 2018 to 2025, to $12B. It turned a profit in 2025 after a loss in 2024.

VRTX has 6 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on VRTX, and all 14 on every stock.Get in free →

VRTX RSI today: 57.8, above its 50-day and 200-day averages

Not scored

RSI 57.8, MACD above signal, above both averages. Not scored.

The deep dive on VRTX

8 more findings on VRTX, each with its source, for Pro members.

VRTX share count over time

Shares: 0.8% fewer than a year ago (to Sep 30).

Shares of VRTX outstanding, as filed
Shares
outstanding
As
of
253.5MOct 31, 2026
253.5MJul 31, 2026
253.8MApr 30, 2026
254MFeb 6, 2026
Offerings, shelves, and splits of VRTX, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Feb 13, 2025

VRTX insider trades

VRTX trades by Congress and the executive branch

20 trades disclosed in the last six months. The newest:

SellRo Khanna$1K to $15KHousetraded Oct 7, disclosed Nov 5(29 days later)
All 20 trades on VRTX disclosed by Congress and the executive branch, for Pro members.Get in free →

See what Congress is buying across the market

VRTX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

15 more officers and directors file at VRTX.

See insider trades by person

Which ETFs hold VRTX?

In ETFs: VRTX is 1.6% of JEPI, 0.7% of JEPQ, and 0.7% of QQQI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex is focused on diversifying its portfolio through Casgevy (gene-editing therapy for beta thalassemia and sickle-cell disease), Journavx (non-opioid pain drug for moderate-to-severe acute pain), and Palsonify (for acromegaly). Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases, cell therapies to deliver a functional cure for type 1 diabetes, povetacicept (for IgA nephropathy).

6,400 employeesBoston, MAvrtx.com

What Vertex Pharmaceuticals says it competes with

“The pharmaceutical industry is characterized by extensive research efforts, rapid technological progress, and intense competition.”

From its annual report, SEC filing · Feb 13, 2026

Here is what Pro members see.

  • The same page for Pro members, on Microsoft

    Its Quality Score and rank, the line that drives it, and the live price.

  • The full chart

    A year of candles to start, out to the whole history, with insider trades marked and the Quality Score under the price.

  • Every line of the score

    Price action, the company, and signals, each with its points, on VRTX and every other stock.

  • FDA dates, counted down

    Each date in the company's words, its cash against the date, and an optional alert before it.

  • CEOs buying their own stock

    Every CEO buy, biggest names first. Sort, filter, save the list, and set optional alerts.

  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

  • The top 10, every day

    The ten highest Quality Scores at each close, kept day by day, week by week.

  • Optional alerts, your way

    Pick a stock, a score, a price, a filing, or a whole scan. It tells you by push or email.

  • Your watchlist, scored

    Your stocks by Quality Score, today's move, or name.

  • On your phone and your laptop

    The same account and watchlist on both, each laid out for its screen.

  • Prices refresh every 2.5 seconds during market hours.
  • Optional alerts by push, email, or the bell.
  • Add it to your Home Screen and it opens like an app.

Pro members see every line of every stock's score.

  • What would move VRTX's score: 4 things
  • 4 more filings explained, a plain line each
  • Real-⁠time prices, no delay
BreakawayOct 7Ro Khanna bought VRTX$1K to $15K, disclosed Oct 7

Alerts are optional.

See VRTX's 14 chart checks

See it live, free until Thursday morning. No account. No card. Then keep going with a free account.

Straight AnswersStraight Answers

As of Nov 10, 2026: VRTX's Quality Score is 16 (Excellent), #17 of 281 in Biotech.

What does VRTX's Quality Score say?

VRTX scores 16 today, which Breakaway calls Excellent. It is #17 of 281 in Biotech by Quality Score, with 6 of 14 chart checks firing. Down 4% on Nov 3 while the S&P 500 rose 0.3%. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is VRTX's Quality Score?

VRTX scores 16 today, which Breakaway calls Excellent (15 to 19). That is #17 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind VRTX's 16.

When does VRTX report earnings?

Expected to report Thu Feb 11, after the close, a date Breakaway expects from the company's usual timing; the company has not confirmed it. VRTX closed higher after 2 of its last 4 reports. Past behavior, not a forecast.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

Every US stock, ranked live.

Insider and Congress trades, the chart, and the financials, in one score.

See all 3,168 stocks ranked

See it live, free until Thursday morning. No account. No card. Then keep going with a free account.

What's next for Vertex Pharmaceuticals: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

Breakaway publishes impersonal securities research and analytical tools: one formula, the same score for everyone. It is not personalized investment advice, and nothing here is a recommendation to buy or sell any security.

Market data from a licensed vendor. The age of every quote is shown on the page.

This browser is too old to show this page right. Update it, or open this page in Safari or Chrome.