Syndax Pharmaceuticals (SNDX) logo

Syndax Pharmaceuticals (SNDX) stock

Cancer medicines , market cap $844M

$9.49
-0.63%

As of Tuesday's close · Live for Pro members at the open

Why is SNDX down?

Down 53% in 3 months while the S&P 500 fell 2%.

  • Free cash flow went from -$71.3M in fiscal 2020 to -$323.2M in fiscal 2025.

Sources: Price history, Nov 9, 2026; Annual reports, Dec 31, 2025

−3Long-term trend below a falling 200-day average, down over one year, down over two years

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1 more reason, free with an account →2 more reasons why SNDX is down, from its filings, with the other side, the timeline, and its peers, for Pro members.
Quality Score
-1
Poor
In its industry
#160of 281
Checks firing
1of 14
Trending down
From 52-week high
-62.9%
under its best in a year

SNDX's Quality Score rose 1 point on Tue, Nov 10, to -1. Its high and its low were both higher than the day before.

Follow SNDX's trial news. Pro members can get an alert when Syndax Pharmaceuticals files news, and see its trials, share raises, and its CEO's filings.

Get an alert when SNDX files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ4 2026“…efficacy data from R/R NUP98r acute leukemia patients treated with revumenib in the fourth quarter of 2026…”Trial data · SEC filing · Nov 2
Cash$551M, about 12 quarters (3 years) at the last year's spendingOn Sep 30

Key facts on SNDX

Key facts on SNDX
Since its 2023 highDown 67% a $149.3M loss → a $209.5M loss a year
Latest filing8-K, Nov 2 Reported its quarterly results and reported a change of officers or directors
1 more reason behind SNDX's -1, free with an account →3 more reasons behind SNDX's -1, for Pro members.

SNDX in the news

Tue Nov 3Syndax Announces CFO Transition SEC filing 4:02 PM ET · GlobeNewswire and 2 more SNDX closed +9.1% that day.

1 more big story on SNDX in the past 12 months, for Pro members.

What's next

Tue Nov 10: Guggenheim 3rd Annual Global…Investor conference · date confirmed.

Expected to report Thu Feb 25, after the close

After its last 4 reports it closed +1.9% on average, higher 3 of 4 times.

4 more dates ahead: conferences, for Pro members.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

Cash$551M, about 12 quarters (3 years) at the last year's spendingOn Sep 30

SNDX catalysts

Coming up

7 more coming up and 19 past catalysts since 2020, with sizes and sources, for Pro members.

What's next for SNDX, and how long its cash lasts

Next step the company has named

Q4 2026“The Company expects to publish safety and efficacy data from R/R NUP98r acute leukemia patients treated with revumenib in the fourth quarter of 2026.”Trial data · SEC filing · Nov 2

What it means: the first look at a trial’s main results, as the company reports them.

Lead program
Revumenib · Acute Myeloid Leukemia · Phase 1/2
Its trial
AUGMENT-101Phase 1/2 · Recruiting · 447 people · main data estimated Dec 15, 2027 · NCT04065399

5 more trials, 8 more milestones and 30 filings, for Pro members.

Cash runway Sep 30 balance sheet

About 12 quarters

$551M in cash and investments (as the company counts them), at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money.

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Feb 27, 2024)
  • At-the-market share sales program (S-3ASR, filed Feb 27, 2024)

For Pro members: 1 raise and its amount, and the share count against a year ago.

Insiders

Director Dennis Podlesak sold 8,000 shares on Oct 29, under a planned sale. 8 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Michael Metzger’s 10 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

How SNDX ranks in Biotech

SNDX is #160 of 281 by Quality Score.

How SNDX ranks in Biotech
RankStockQuality Score
160Syndax Pharmaceuticals (SNDX) logoSNDXSyndax Pharmaceuticals-1

More in Biotech

When does SNDX report earnings, and what happens after?

Expected to report Thu Feb 25, after the close (in 107 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What SNDX reported on Nov 2, 2026

The quarter

Sales of $83.3M, 82% more than a year ago.

“Revuforj net revenue grew to $61 million, driven by a 20% increase in new patients and an increasing number of patients on therapy in the post-transplant setting.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

Where the quarter's sales came from
LineQ3
2026
Q2
2026
Q3
2025
By product
Productup 90%$60.7M73%$54.7M75%$32M70%

Each quarter's sales and their share of its total. Figures as filed (SEC filing, Nov 2)

1 more line, for Pro members.

The outlook

The outlook the company gave, by period
MeasureFigure
Full year 2026
Total research and development plus selling, general and administrative expensesabout $400Mkept

Figures as filed (SEC filing, Nov 2)

In the company's words

  • “Syndax expects that its cash, cash equivalents and short- and long-term investments, combined with its anticipated product revenue, collaboration revenue and interest income, will enable the Company to reach profitability.”

From its results filing (SEC filing · Nov 2)

1 more sentence, for Pro members.

The numbers

Market value
$844M
today
Sales
$290M
up 160% on the year

Its share count grew 16% a year over 5 years.

2 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on SNDX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-10.8%+4.4%+9.1%
Apr 30Aug 4Nov 2
ReportedGapReaction5
days
Nov 2, 2026After close-0.1%+9.1%-27.1%
Aug 4, 2026After close-9.3%+4.4%+6.3%
Apr 30, 2026After close-2.8%-10.8%-4.2%

SNDX closed higher after 3 of its last 4 reports.

All 4 reports, and SNDX's Quality Score going into each

SNDX sales and profit by year

Sales and profit by year

Sales grew in three of the last seven years, to $172M in 2025. It made a profit in one of the eight years.

SNDX has 1 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on SNDX, and all 14 on every stock.Get in free →

SNDX RSI today: 25.8, below its 50-day and 200-day averages

Not scored

RSI 25.8, MACD below signal, below both averages. Not scored.

The deep dive on SNDX

7 more findings on SNDX, each with its source, for Pro members.

SNDX share count over time

4% more shares than a year earlier.

Weighted shares, quarter to Sep 30, 2026, both from one filing

Shares of SNDX outstanding, as filed
Shares
outstanding
As
of
89.3MJul 31, 2026
88.6MApr 27, 2026
88.2MFeb 23, 2026
86.9MOct 31, 2025
Offerings, shelves, and splits of SNDX, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Feb 27, 2024
Raised $200M in a sale of shares, about 24% of its market valueDec 15, 2023

SNDX insider trades

2 insiders sold $152K across 2 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellMichael A. Metzger$130KChief Executive Officerat $18.99 on Jun 1, filed Jun 2

SNDX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

3 more officers and directors file at SNDX.

See insider trades by person

Which ETFs hold SNDX?

In ETFs: SNDX is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Syndax Pharmaceuticals

Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.

298 employeesNew York, NYsyndax.com

Here is what Pro members see.

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  • Every line of the score

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  • FDA dates, counted down

    Each date in the company's words, its cash against the date, and an optional alert before it.

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  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

  • The top 10, every day

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Pro members see every line of every stock's score.

  • What would turn SNDX's score around: 7 things
  • 4 more filings explained, a plain line each
  • 2 more things pulling SNDX's score down
BreakawayJun 2Michael A. Metzger sold SNDX$130K at $18.99, filed Jun 2

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See SNDX's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: SNDX's Quality Score is -1 (Poor), #160 of 281 in Biotech. Insiders sold $152K in the last 6 months (Form 4).

What does SNDX's Quality Score say?

SNDX scores -1 today, which Breakaway calls Poor. It is #160 of 281 in Biotech by Quality Score, with 1 of 14 chart checks firing. Down 53% in 3 months while the S&P 500 fell 2%. Cash lasts about 12 quarters at its spending (to Sep 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is SNDX's Quality Score?

SNDX scores -1 today, which Breakaway calls Poor (below zero). That is #160 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind SNDX's -1.

Are insiders buying SNDX?

2 insiders sold $152K across 2 filings in the last 6 months. No open-⁠market buys on record. The newest is Michael A. Metzger, Chief Executive Officer, who sold $130K on Jun 1. Every filing, with the scored weight, for Pro members.

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Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

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What's next for Syndax Pharmaceuticals: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

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