Inovio Pharmaceuticals (INO) logo

Inovio Pharmaceuticals (INO) stock

$1.45
-3.97%

DNA medicines, worth $150MSmall-cap biotech

As of Tuesday's close · Live for Pro members at the open

Why is INO down?

Down 16% on Nov 6 while the S&P 500 rose 0.3%.

  • It filed a prospectus for an offering of shares of $61.7M on Nov 6, 2026.

Sources: Price history, Nov 6, 2026; Prospectus supplement, Nov 6, 2026

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1 more reason, free with an account →2 more reasons why INO fell on Nov 6, from its filings, with how the business stands, the timeline, and its peers, for Pro members.
Quality Score
-7
Poor
In its industry
#252of 281
Checks firing
4of 14
Trending down
From 52-week high
-46.7%
under its best in a year

INO's Quality Score was unchanged on Tue, Nov 10, at -7.

Follow INO's trial news. Pro members can get an alert when Inovio Pharmaceuticals files news, and see its trials, share raises, and its CEO's filings.

Get an alert when INO files news on its trialSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Next2026“In anticipation of a potential approval in 2026, INOVIO is preparing its commercial launch activities.”Regulatory decision · SEC filing · Aug 12

Key facts on INO

Key facts on INO
Holding it back110.2% more shares than a year ago
Latest filing8-K, Nov 10 Reported its quarterly results
1 more reason behind INO's -7, free with an account →5 more reasons behind INO's -7, for Pro members.

INO in the news

ReportToday after the close: a loss of $0.50 a share. Past reports ›

Mon Nov 9Form 8K Inovio Pharmaceuticals Inc For: 9 November By Investing.com ca.investing.com and 1 more INO closed +24.3% that day.

What's next

Expected to report Thu Mar 11, after the close

After its last 3 reports it closed +5.7% on average, higher 2 of 3 times.

INO catalysts

Coming up

8 past catalysts since 2021, with sizes and sources, for Pro members.

What's next for INO, and how long its cash lasts

Next step the company has named

2026“In anticipation of a potential approval in 2026, INOVIO is preparing its commercial launch activities.”Regulatory decision · SEC filing · Aug 12

What it means: a regulator’s decision on an application to sell the drug.

A trial underway
INO-5401 and INO-9012 Delivered by Electroporation in Combination With Cemiplimab in Newly-Diagnosed GlioblastomaPhase 1/2 · Active · 52 people · main data estimated Dec 31, 2027 · NCT03491683

For Pro members: 31 filings.

Cash runway

The company says its cash lasts into late fourth quarter 2027 (8-K, Nov 9).

That is the company's estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3, filed Jul 2, 2026)
  • At-the-market share sales program (S-3, filed Jul 2, 2026)

For Pro members: 7 raises and their amounts, and the share count against a year ago.

Insiders

No open-market buys or sales by its officers or directors in their filings of the last year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Jacqueline Shea’s 15 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why INO scores -7

Poorfor quality, not price, 4 of 14 chart checks firingWhat the Quality Score means

-7 is below -5, off the left end of the scale.

  • +4Chart checks 4 of 14 firing right now, one point each
  • −3News dilutive offering, earnings release, material agreement
  • Long-term trend subtracts
  • Size subtracts
  • Growth subtractsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Dilution subtractsNew shares over the year: -1 at 10% more, -2 at 25% more.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Run-up, Profit, and Persistence.

What every line is worth, and the reason behind it, on INO and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 10:56 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How INO ranks in Biotech

INO is #252 of 281 by Quality Score.

How INO ranks in Biotech
RankStockQuality Score
252Inovio Pharmaceuticals (INO) logoINOInovio Pharmaceuticals-7

Net income over four quarters: INO -$67.4M, NRXP -$23.5M, SVRA -$153M.

More in Biotech

When does INO report earnings, and what happens after?

Expected to report Thu Mar 11, after the close (in 121 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What INO reported on Nov 10, 2026

The quarter

A loss of $0.50 a share, from $0.87.

“The increase in net loss was primarily driven by a $26.9 million non-cash loss on fair value adjustment related to our warrant liabilities for the three months ended September 30, 2026, compared to a $22.5 million non-cash loss for the same period in 2025.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

INO's results filing gives no sales by line in a table we read.

The outlook

The outlook the company gave, by period
MeasureFigure
Q4 2026
Operational net cash burnabout $21M

Figures as filed (SEC filing, Nov 10)

In the company's words

  • “The increase was due to the anticipated launch of VOCERYQ.”

From its results filing (SEC filing · Nov 10)

The numbers

Market value
$150M
today
Sales
$0
down 100% on the year
Free cash flow
-$80.8M
last 12 months

1 more figure, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on INO: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-1.2%+1.5%+16.9%
Mar 12May 13Aug 12
ReportedGapReaction5
days
Aug 12, 2026After close+5.2%+16.9%+68.8%
May 13, 2026After close-3.7%+1.5%-8.2%
Mar 12, 2026After close+2.4%-1.2%-1.8%

INO closed higher after 2 of its last 3 reports.

INO sales and profit by year

Sales and profit by year

Sales grew in two of the last seven years, to $65K in 2025. It lost money in each of the eight years.

INO has 4 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on INO, and all 14 on every stock.Get in free →

INO RSI today: 56.1, above its 50-day and 200-day averages

Not scored

RSI 56.1, MACD above signal, above both averages. Not scored.

The deep dive on INO

  • What it does and how it makes money3 findingsAn operating loss of $86.8M in fiscal 2025, on $65K of sales.Annual report, filed Mar 12, 2026"In the event that VGX-3100 is approved for marketing, we will be entitled to receive royalty payments based on a tiered percentage of annual net sales, with such percentage being in the low- to mid-teens, subject to reduction in the event of generic competition in a particular territory." (10-K for fiscal 2025)SEC filing · Mar 12, 2026
  • Where it stands1 findingFor Pro members1 finding on where INO stands: its cash, debt, and share count, for Pro members
  • What changed in its filings11 findings"On June 3, 2020, the Company filed a complaint in the Court of Common Pleas of Montgomery County, Pennsylvania against VGXI, Inc. and GeneOne Life Science, Inc., or GeneOne, collectively referred to as 'VGXI', alleging that VGXI materially breached the Company’s supply agreement." (10-Q for the quarter to Jun 30, 2026)SEC filing · Aug 12, 2026A new heading in its "Risk Factors" this year: "We do not currently have sufficient working capital to fund our planned operations for the next twelve months and substantial doubt exists as to our ability to continue as a going concern. Our historical financial statements have been prepared under the assumption that we will continue as a going concern." (10-K for fiscal 2025; not in fiscal 2024's)SEC filing · Mar 12, 2026, against the one of Mar 18, 2025
  • Who holds and trades it1 findingFor Pro members1 finding on who holds and trades INO, for Pro members
  • Against its closest peers2 peersNet income over four quarters: INO -$67.4M, NRXP -$23.5M, SVRA -$153M.

12 more findings on INO, each with its source, for Pro members.

INO share count over time

Shares: 2.1 times the count a year ago (to Jun 30).

Shares of INO outstanding, as filed
Shares
outstanding
As
of
103.4MAug 10, 2026
82.3MMay 12, 2026
69.1MMar 12, 2026
53.6MNov 7, 2025
Offerings, shelves, and splits of INO, from its filings
From its
filings
Filed
Raised $61.7M in a sale of shares, about 41% of its market valueNov 6, 2026
Raised $20M in a sale of shares, about 13% of its market valueJul 30, 2026
Registered shares for a later sale (S-3)Jul 2, 2026
Raised $17.5M in a sale of shares, about 12% of its market valueApr 2, 2026

4 more offerings on file, for Pro members.

INO's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold INO?

In ETFs: INO is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Inovio Pharmaceuticals

Inovio Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from diseases associated with human papillomavirus (HPV), cancer and infectious diseases. INOVIO's platform harnesses the power of in vivo protein production, featuring optimized design and delivery of DNA medicines that teach the body to manufacture its own disease-fighting tools. Its candidate is INO-3107 for the treatment of recurrent respiratory papillomatosis (RRP), a chronic, rare and debilitating disease of the respiratory tract caused by HPV infection. In its completed Phase 1/2 clinical trial of INO-3107 for the treatment of HPV-6 and HPV-11-associated RRP.

112 employeesPlymouth Meeting, PAinovio.com

What Inovio Pharmaceuticals says it competes with

“As we develop and seek to ultimately commercialize our product candidates, we face and will continue to encounter competition with an array of existing or development-stage drug and immunotherapy approaches targeting diseases we are pursuing.”

From its annual report, SEC filing · Mar 12, 2026

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Straight AnswersStraight Answers

As of Nov 10, 2026: INO's Quality Score is -7 (Poor), #252 of 281 in Biotech.

What does INO's Quality Score say?

INO scores -7 today, which Breakaway calls Poor. It is #252 of 281 in Biotech by Quality Score, with 4 of 14 chart checks firing. Down 16% on Nov 6 while the S&P 500 rose 0.3%. Shares: 2.1 times the count a year ago (to Jun 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is INO's Quality Score?

INO scores -7 today, which Breakaway calls Poor (below zero). That is #252 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind INO's -7.

When does INO report earnings?

Expected to report Thu Mar 11, after the close, a date Breakaway expects from the company's usual timing; the company has not confirmed it. INO closed higher after 2 of its last 3 reports. Past behavior, not a forecast.

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What's next for Inovio Pharmaceuticals: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

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