Harmony Biosciences Holdings (HRMY) logo

Harmony Biosciences Holdings (HRMY) stock

Rare disease medicines , market cap $1.9B

$33.55
-0.68%

As of Tuesday's close · Live for Pro members at the open

Why is HRMY down?

Down 13% from Oct 30 to Nov 10.

  • It fell 7% on Nov 4, when cost of product sold rose to $80.7M from $59.7M a year before.

Sources: Price history, Nov 10, 2026; Company release, Nov 4, 2026

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1 more reason, free with an account →2 more reasons why HRMY fell 13% since Oct 30, from its filings, with the other side, the timeline, and its peers, for Pro members.
Quality Score
4
Below Average
In its industry
#84of 281
Checks firing
2of 14
Trending up
From 52-week high
-22.9%
under its best in a year

HRMY's Quality Score fell 1 point on Tue, Nov 10, to 4. Its down days drew more trading than its up days lately (3 chart checks stopped).

Follow HRMY's trial news. Pro members can get an alert when Harmony Biosciences Holdings files news, and see its trials, share raises, and its CEO's filings.

Get an alert when HRMY files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ1 2027“…remains on track to report Phase 1b data in sleep-deprived healthy volunteers in the first quarter of 2027…”Trial data · SEC filing · Nov 4

Key facts on HRMY

Key facts on HRMY
Since its 2022 highDown 45% profit $181.5M → $178.6M a year
Latest filing8-K, Nov 4 Reported its quarterly results

HRMY in the news

Wed Nov 4Harmony Biosciences reported diluted EPS of $0.81 SEC, 8:00 AM ET HRMY closed −7.0% that day.

Big story

Mon Oct 12: Leadership

Harmony Biosciences Stock Dives As CEO Jeffrey Dayno Plans His Exit

HRMY closed −5.1% that day.

Reported by Investor's Business Daily · covered by 11 outlets

Get an alert on HRMY's next big story →

Outlet counts from the GDELT Project. The move is what HRMY did that session, not a claim about why.

HRMY catalysts

Coming up

After its last 4 reports it closed +0.7% on average, higher 2 of 4 times.

7 more coming up and 13 past catalysts since 2023, with sizes and sources, for Pro members.

What's next for HRMY

Next step the company has named

Q1 2027“Harmony remains on track to report Phase 1b data in sleep-deprived healthy volunteers in the first quarter of 2027, followed by the initiation of Phase 2 studies across multiple CNS…”Trial data · SEC filing · Nov 4

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Pitolisant in Patients With Prader-Willi SyndromePhase 3 · Recruiting · 134 people · main data estimated Apr 2027 · NCT06366464

4 more trials, 5 more milestones and 35 filings, for Pro members.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Feb 25, 2025)
  • At-the-market share sales program (S-3ASR, filed Feb 25, 2025)

For Pro members: the amounts, and the share count against a year ago.

Insiders

Chief Medical Officer Kumar Budur sold 38,452 shares on Sep 18. 3 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Jeffrey Dayno’s 5 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why HRMY scores 4

Below Averagefor quality, not price, 2 of 14 chart checks firingWhat the Quality Score means

  • +2Chart checks 2 of 14 firing right now, one point each
  • +1Long-term trend below a rising 200-⁠day average
  • Profit addsRead on the last four quarters against the four before, or the last full year where no quarters are filed.

No effect today: Run-up, Size, Growth, Dilution, Volatility, Cash flow, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on HRMY and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 10:45 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How HRMY ranks in Biotech

HRMY is #84 of 281 by Quality Score.

How HRMY ranks in Biotech
RankStockQuality Score
84Harmony Biosciences Holdings (HRMY) logoHRMYHarmony Biosciences4

More in Biotech

When does HRMY report earnings, and what happens after?

Expected to report Tue Feb 23, before the open (in 105 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What HRMY reported on Nov 4, 2026

The quarter

A profit of $0.81 a share, from $0.87.

“The increase in cost of product sold as a percentage of net product revenue was primarily driven by new royalties related to the Novitium license agreement.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

HRMY's results filing gives no sales by line in a table we read.

The outlook

The outlook the company gave, by period
MeasureFigure
Full year 2026
WAKIX net revenue$1.00B to $1.04Bkept

Figures as filed (SEC filing, Nov 4)

In the company's words

  • “The decline in earnings was primarily driven by an increase in milestone charges and the new MSN royalty charges during the third quarter of 2026 as compared to the same quarter in 2025.”

From its results filing (SEC filing · Nov 4)

The numbers

Market value
$1.9B
today
Sales
$989M
up 19.8% on the year

Sales grew 40% a year over 5 years, fiscal 2020 to 2025.

Its share count fell 1.4% a year over 3 years.

4 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on HRMY: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-4.2%+8.9%-7.0%
May 7Aug 4Nov 4
ReportedGapReaction5
days
Nov 4, 2026Before open-6.8%-7.0%-9.4%
Aug 4, 2026Before open+4.2%+8.9%+9.6%
May 7, 2026Before open-11.7%-4.2%-6.0%

HRMY closed higher after 2 of its last 4 reports.

All 4 reports, and HRMY's Quality Score going into each

HRMY sales and profit by year

Sales and profit by year

Sales grew every year from 2019 to 2025, to $868M. It made a profit in five of the seven years.

HRMY has 2 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on HRMY, and all 14 on every stock.Get in free →

HRMY RSI today: 34.1, below its 50-day and 200-day averages

Not scored

RSI 34.1, MACD below signal, below both averages. Not scored.

The deep dive on HRMY

  • What it does and how it makes money6 findingsIt kept 24 cents of each dollar of sales in fiscal 2025: $208M of operating profit on $868M of sales.Annual report, filed Feb 24, 2026"Pursuant to the 2017 LCA, we agreed to pay royalties on the net sales of the product at tiered royalty rates of 13% to 24% based on annual total net sales during the period commencing on first commercial sale of the product and ending on the latest of 10 years from first commercial sale of the product …" (10-K for fiscal 2025)SEC filing · Feb 24, 2026
  • Where it stands2 findingsFor Pro members2 findings on where HRMY stands: its cash, debt, and share count, for Pro members
  • What changed in its filings5 findings"On April 20, 2026, the Company, along with its exclusive licensor Novitium, filed a lawsuit against AET, AET Laboratories Private Limited, Alfred E." (10-Q for the quarter to Sep 30, 2026)SEC filing · Nov 4, 2026A new heading in its "Risk Factors" this year: "Our use of new and evolving technologies, such as artificial intelligence, may present risks and challenges that can impact our business, including by posing cybersecurity and other risks to our confidential and/or proprietary information …" (10-K for fiscal 2025; not in fiscal 2024's)SEC filing · Feb 24, 2026, against the one of Feb 25, 2025Three Customers made up 100% of its revenue in fiscal 2025, the same as in fiscal 2024.SEC filing · Feb 24, 2026
  • Who holds and trades it3 findingsFor Pro members3 findings on who holds and trades HRMY, for Pro members

11 more findings on HRMY, each with its source, for Pro members.

HRMY share count over time

Shares: 1.5% more than a year ago (to Sep 30).

Shares of HRMY outstanding, as filed
Shares
outstanding
As
of
58.7MNov 2, 2026
58.2MJul 31, 2026
57.9MMay 5, 2026
57.8MFeb 20, 2026
Offerings, shelves, and splits of HRMY, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Feb 25, 2025

HRMY insider trades

One insider sold $3.1M across 7 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellKumar Budur$1.5MChief Medical Officerat $43.05 on Sep 18, filed Sep 18

All 7 insider filings on HRMY from the last six months, for Pro members.

All HRMY insider trades

HRMY's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold HRMY?

In ETFs: HRMY is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Harmony Biosciences Holdings

Harmony Biosciences Holdings Inc is a commercial-stage pharmaceutical company focused on developing and commercializing therapies for patients living with rare neurological diseases who have unmet medical needs. The company has one reportable segment: rare neurological diseases. Its product WAKIX (pitolisant) is a molecule with a novel mechanism of action specifically designed to increase histamine signaling in the brain by binding to H3 receptors and is used for the treatment of cataplexy in adult patients with narcolepsy. The other drug candidates in its pipeline are Pitolisant, HBS-102 (MCHR1 antagonist), BP1.15205 (orexin-2 receptor agonist), ZYN002 (cannabidiol gel), EPX-100 (clemizole hydrochloride), and EPX-200 (lorcaserin), among others.

293 employeesPlymouth Meeting, PAharmonybiosciences.com

What Harmony Biosciences Holdings says it competes with

“Our industry is highly competitive and subject to rapid and significant change as research provides a deeper understanding of rare neurological disorders, including narcolepsy, and as new therapies are developed.”

From its annual report, SEC filing · Feb 24, 2026

Here is what Pro members see.

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  • What would turn HRMY's score around: 6 things
  • 5 more filings explained, a plain line each
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BreakawaySep 18Kumar Budur sold HRMY$1.5M at $43.05, filed Sep 18

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See HRMY's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: HRMY's Quality Score is 4 (Below Average), #84 of 281 in Biotech. Insiders sold $3.1M in the last 6 months (Form 4).

What does HRMY's Quality Score say?

HRMY scores 4 today, which Breakaway calls Below Average. It is #84 of 281 in Biotech by Quality Score, with 2 of 14 chart checks firing. Down 13% from Oct 30 to Nov 10. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is HRMY's Quality Score?

HRMY scores 4 today, which Breakaway calls Below Average (0 to 5). That is #84 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind HRMY's 4.

Are insiders buying HRMY?

One insider sold $3.1M across 7 filings in the last 6 months. No open-⁠market buys on record. The newest is Kumar Budur, Chief Medical Officer, who sold $1.5M on Sep 18. Every filing, with the scored weight, for Pro members.

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What's next for Harmony Biosciences Holdings: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

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