Structure Therapeutics (GPCR) stock

Market cap $2.1B

$27.67
-4.52%

Market closed. Prices as of today's close.

Quality Score
-7
Poor
In its industry
#281of 300
NextQ4 2026“Additional clinical data expected in the fourth quarter of 2026 could”Trial data · 8-K, Sep 8
Cash$1.3B in cash. One of the last four quarters brought cash in while the others used it.On Jun 30 · the company says “through 2028”

Follow GPCR's trial news. Pro members can get an alert when Structure Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an optional alert when GPCR files news on its trialsFree for 24 hours. No account needed.

GPCR's Quality Score fell 1 point on Fri, Oct 2, to -7.

Cash$1.3B in cash. One of the last four quarters brought cash in while the others used it.On Jun 30 · the company says “through 2028”
Pipeline and cash

What's next for GPCR, and how long its cash lasts

From Structure Therapeutics’s SEC filings and ClinicalTrials.gov: the company’s own words, the registry’s dates, and arithmetic, not a forecast. Companies often miss their own dates.

Next step the company has named

Q4 2026“Additional clinical data expected in the fourth quarter of 2026 could”Trial data · 8-K, Sep 8

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related ComorbidityPhase 3 · Recruiting · 3,600 people · main data estimated Sep 2028 · NCT07654361

4 more trials, 5 more milestones and 27 filings, for Pro members.

Cash runway Jun 30 balance sheet

$1.3B in cash

One of the last four quarters brought cash in while the others used it, so an average says little about the next.

What it means: a runway is counted only when each of the last four quarters used cash. The company's own estimate is “through 2028” (8-K, Sep 8).

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Aug 6, 2025)
  • At-the-market share sales program (424B5, filed May 7, 2026)

A shelf lets a company sell shares later; an at-the-market program sells them into the market over time. Neither is a sale by itself.

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

No open-market buys or sales by its officers or directors in their filings of the last year.

From their own Form 4 filings: buys and sales in the market, not awards or shares withheld for tax.

For Pro members: every trade, and Raymond Stevens’s 11 filings and quotes.

See every upcoming FDA date →

Biotech dates

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their own filings, soonest first and small companies first.

DateStockDrug

8 more FDA dates and 114 trial data dates in the next 60 days. Pro members see every one, with the cash against its date and an optional alert before it. Get in free →

Why GPCR is down

Structure Therapeutics fell 19.5% over the five sessions to Oct 1.

Biotech stocks fell a median 3.4% and the S&P 500 fell 0.4% in those sessions; Structure Therapeutics fell 19.5%.

Sources: Price history, Oct 1, 2026

−2Long-term trend below a falling 200-day average, down over two years

1 more driver, the timeline, and the peer table, for Pro members

4 more things pulling GPCR's score down, for Pro members

What's next

Expected to report Thu Nov 5, after the close

After its last 4 reports it closed -0.9% on average, higher 1 of 4 times.

What would turn GPCR's score around: 8 things, for Pro members

Alert me when GPCR's Quality Score turns up

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Pro

Here is what Pro members see.

Every stock has a live page like this, GPCR included: the price in real time, the full chart, all 14 checks, and every line of its score.

AMD's page for Pro members on a phone, recorded live: the price changes as it trades, beside its Quality Score and its rank, with the bid and ask under it and a year of candles below
The same page for Pro members, on AMDThe live price and the full chart, with the Quality Score drawn under it and the line that drives it.
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Every line of the scoreWhat each part adds, and all 14 checks by group, on GPCR and every other stock.
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The 14 checks

Nothing is firing on GPCR right now

One per group is shown here.

Trend1 of 5 shown

Averages stacked in order, price near its high.

Volume1 of 3 shown

Heavy volume on the run, quiet volume at rest.

Tight range1 of 3 shown

The daily range is tight against its own recent history.

Buying1 of 3 shown

Closes near the high, and buyers step in on dips.

The other 10 checks on GPCR, and all 14 on every stock.Get in free →

Also on the chart

Not scored

Shown for reference. None of these counts toward the Quality Score: in our tests on 20 years of daily prices, none of them improved it.

  • RSI 1416.8

    Below 30.

  • MACD (12, 26, 9)Below signal

    Crossed below its signal line 30 sessions ago.

  • The price is 38.1% below it.

  • The price is 48.3% below it. The 50-day is below the 200-day, since May 26.

  • ADX 1444.4

    25 or more, with +DI below -DI.

  • Support$25.59

    Swing low from Oct 22, 2025, 7.5% below the price.

  • Swing high from Oct 15, 2025, 12.3% above the price.

  • The bands run from $27.85 to $44.89.

  • Volume1.1x

    Against its 20-day average, for the time of day.

Its industry

How GPCR ranks in Biotech

GPCR is #281 of 300 by Quality Score. The top three are shown with their scores, and more by name.

More in Biotech, on the Healthcare page

Earnings

When does GPCR report earnings, and what happens after?

Expected to report Thu Nov 5, after the close (in 34 days). Not yet confirmed by the company.

ReportedGapReaction5 sessions
Aug 6, 2026After close+2.2%+1.0%+4.0%
May 7, 2026After close-2.5%-0.1%+1.8%
Feb 26, 2026After close-1.0%-2.7%-7.8%
Nov 6, 2025After close+0.7%-1.9%+4.6%

The gap is the next open against the close before the report; the reaction is where that session closed. GPCR closed higher after 1 of its last 4. Past behavior, not a forecast.

Report dates and past reactions come from sessions that have already closed, so none of these figures move.

The company

About Structure Therapeutics

Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.

281 employeesSouth San Francisco, CAstructuretx.com

Pro

Every line of the score, on every stock.

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  • Every line of GPCR's score, with the points and the reason
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Questions

Straight Answers.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, trial included, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

Where does the data come from?

Daily bars, quotes, reference data, headlines, and short interest come from Massive, formerly Polygon, a licensed market data vendor. The age of the quotes is shown at the top of every page. Insider trades, notable holders and profits come straight from the SEC. That means Form 4 filings, 13F filings and XBRL financial data on EDGAR. Government filings come from the public STOCK Act and Office of Government Ethics disclosures. The market-wide headlines on the market line also come from the public headline feeds CNBC, MarketWatch and Yahoo Finance publish, shown as the headline, the source and a link to the article. Splits, dividends, and the financial statements on each ticker page come from the vendor's reference data. The 8-K filings on EDGAR are read for the items that move a price. Five years of history is loaded for every stock. So the 200-day and 52-week checks rest on real history. Options flow is not part of the product.

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Is this investment advice?

No. It is a screening tool that scores stocks on the chart, the company's own results, and the news and filings. It does not know your situation and it is not a recommendation to buy or sell anything. Please do your own research.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes. Filings are shown as filed, because a disclosure is already days or weeks old when it becomes public. Earnings dates and past reactions are settled sessions.