Definium Therapeutics (DFTX) logo

Definium Therapeutics (DFTX) stock

Psychiatric therapeutics , market cap $4.1B

$34.64
-2.12%

As of Tuesday's close · Live for Pro members at the open

Quality Score
-1
Poor
In its industry
#150of 281
Checks firing
1of 14
Choppy
From 52-week high
-30.3%
under its best in a year

DFTX's Quality Score fell 1 point on Tue, Nov 10, to -1. It closed away from its high of the day.

Follow DFTX's trial news. Pro members can get an alert when Definium Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an alert when DFTX files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

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Next1H 2027“On track for DT120 ODT NDA filing in first half of 2027”Filing with regulators · SEC filing · Nov 9

Why DFTX rose 14% since Nov 5

Up 14% from Nov 5 to Nov 10.

  • Definium Therapeutics rose 14% from Nov 5 to Nov 10. 10 points of it came on Nov 6.

Sources: Price history, Nov 10, 2026

1 more reason, free with an account →2 more reasons why DFTX rose 14% since Nov 5, from its filings, with the timeline and its peers, for Pro members.

Key facts on DFTX

Key facts on DFTX
Holding it back58.3% more shares than a year ago
Latest filing8-K, Nov 9 Reported its quarterly results
1 more reason behind DFTX's -1, free with an account →4 more reasons behind DFTX's -1, for Pro members.

DFTX in the news

ReportLast night: the results are out. Past reports ›

What's next

Tue Nov 10: Stifel Healthcare Conference 2026Investor conference · date confirmed.

3 more dates ahead: conferences, for Pro members.

DFTX catalysts

Coming up

After its last 4 reports it closed -1.5% on average, higher 1 of 4 times.

3 more coming up and 5 past catalysts since 2026, with sizes and sources, for Pro members.

What's next for DFTX, and how long its cash lasts

Next step the company has named

1H 2027“On track for DT120 ODT NDA filing in first half of 2027”Filing with regulators · SEC filing · Nov 9

What it means: a filing asks regulators to approve a drug for sale. Once it is complete and accepted, the FDA sets a decision date, and we show it here.

Lead program
DT120 · Major Depressive Disorder · Phase 3
Its trial
DT120 for Major Depressive Disorder (Ascend)Phase 3 · Recruiting · 165 people · main data estimated Sep 2027 · NCT07592689

4 more trials, 2 more milestones and 44 filings, for Pro members.

Cash runway

The company says its cash lasts into 2030 (8-K, Nov 9).

That is the company's estimate. Our arithmetic on its latest balance sheet reads differently, so we show its words, not ours.

For Pro members: the cash on hand, the cash used each quarter, and the math.

Dilution on the horizon

No shelf registration or at-the-market program on file in the last three years.

For Pro members: 4 raises and their amounts, and the share count against a year ago.

Insiders

Chief Medical Officer Daniel Karlin sold 10,853 shares on Sep 25, under a planned sale. 13 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Robert Barrow’s 24 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why DFTX scores -1

Poorfor quality, not price, 1 of 14 chart checks firingWhat the Quality Score means

  • +2Run-up 64% over 6 months
  • −2Dilution 58.3% more shares outstanding than a year agoNew shares over the year: -1 at 10% more, -2 at 25% more.
  • Chart checks adds
  • Long-term trend adds
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Size, Growth, Persistence, and News.

What every line is worth, and the reason behind it, on DFTX and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:18 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How DFTX ranks in Biotech

DFTX is #150 of 281 by Quality Score.

How DFTX ranks in Biotech
RankStockQuality Score
150Definium Therapeutics (DFTX) logoDFTXDefinium Therapeutics-1

Share count against a year before: DFTX +58%, RGC +0%.

More in Biotech

When does DFTX report earnings, and what happens after?

Expected to report Thu Mar 4, after the close (in 114 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What DFTX reported on Nov 9, 2026

The quarter

The figures are not read from the release yet.

“The decrease in net loss was primarily attributable to a gain from the change in fair value of the Company’s 2022 USD financing warrants and higher interest income, partially offset by increased operating expenses.”

The filing on EDGAR

Where the sales came from

DFTX's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The increase was primarily attributable to an $8.8 million increase in personnel-related costs associated with the expansion of the Company’s research and development organization, a $5.9 million increase in expenses related to the DT120 development program, and a $0.6 million increase in preclinical and other program expenses, partially offset by a $0.2 million decrease in DT402 program expenses.”

From its results filing (SEC filing · Nov 9)

1 more sentence, for Pro members.

The numbers

Market value
$4.1B
today

No analyst estimates on Breakaway: every figure here is filed.

The whole report on DFTX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

-5.0%0.0%-2.1%
May 7Aug 6Nov 9
ReportedGapReaction5
days
Nov 9, 2026After close-2.7%-2.1%not yet
Aug 6, 2026After close+0.3%0.0%-4.8%
May 7, 2026After close-1.5%-5.0%-8.0%

DFTX closed higher after 1 of its last 4 reports.

All 4 reports, and DFTX's Quality Score going into each

DFTX has 1 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on DFTX, and all 14 on every stock.Get in free →

DFTX RSI today: 48.4, below its 50-day, above its 200-day

Not scored

RSI 48.4, MACD above signal, below its 50-day, above its 200-day. Not scored.

The deep dive on DFTX

6 more findings on DFTX, each with its source, for Pro members.

DFTX share count over time

Shares: 58.3% more than a year ago (to Sep 30).

Shares of DFTX outstanding, as filed
Shares
outstanding
As
of
136.9MNov 2, 2026
134.4MJul 30, 2026
109.1MApr 30, 2026
99.7MFeb 19, 2026
Offerings, shelves, and splits of DFTX, from its filings
From its
filings
Filed
Priced a sale of sharesJun 24, 2026
Priced a sale of sharesOct 31, 2025
Priced a sale of sharesAug 12, 2024
Registered shares for a later sale (S-3ASR)Jun 28, 2024

DFTX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

3 more officers and directors file at DFTX.

See insider trades by person

About Definium Therapeutics

Definium Therapeutics Inc is developing inventive, next-generation therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. Its late-stage pipeline includes four Phase 3 trials-two each for GAD and MDD-anchored by its candidate, DT120 ODT, which has received FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is advancing its commercial and operational readiness to support a care model and prepare for the potential launch of DT120 ODT, if approved and marketed. The company operates in one reportable segment relating to the research and development of the company's neurological drug development platform.

106 employeesNew York, NYdefiniumtx.com

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See DFTX's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: DFTX's Quality Score is -1 (Poor), #150 of 281 in Biotech.

What does DFTX's Quality Score say?

DFTX scores -1 today, which Breakaway calls Poor. It is #150 of 281 in Biotech by Quality Score, with 1 of 14 chart checks firing. Up 14% from Nov 5 to Nov 10. Shares: 58.3% more than a year ago (to Sep 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is DFTX's Quality Score?

DFTX scores -1 today, which Breakaway calls Poor (below zero). That is #150 of 281 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind DFTX's -1.

When does DFTX report earnings?

Expected to report Thu Mar 4, after the close, a date Breakaway expects from the company's usual timing; the company has not confirmed it. DFTX closed higher after 1 of its last 4 reports. Past behavior, not a forecast.

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What's next for Definium Therapeutics: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

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