Zymeworks (ZYME) logo

Zymeworks (ZYME) stock

Biotherapeutics , market cap $2.1B

Close
$28.99
+1.33%

After-hours $28.99 0.00%

As of 4:03 PM ET after-hours, delayed 15+ min · Live for Pro members

Quality Score
7
Average
In its industry
#22of 92

ZYME's Quality Score rose 1 point on Fri, Oct 30, to 7. Traded heavy volume (2 chart checks started).

Follow ZYME's trial news. Pro members can get an alert when Zymeworks files news, and see its trials, share raises, and its CEO's filings.

Get an alert when ZYME files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Next2026“…for projected durable revenue growth ZW191 & ZW251 Phase 1 trials initiated ZW209 IND anticipated in 2026…”Filing with regulators · SEC filing · Jun 29
Cash$322M, about 10 quarters (2.5 years) at the last year's spendingOn Jun 30 · the company says “beyond 2028”

Why is ZYME up?

Up 309% over three years while the S&P 500 rose 89%.

“Total revenue increased by $29.7 million in 2025 compared to 2024, due to higher revenue recognized across multiple partnered programs.”

Its fiscal 2025 10-K said

Sources: Price history, Oct 30, 2026; Annual report (10-K), Mar 2, 2026

1 more reason, free with an account →2 more reasons why ZYME beats the market, from its filings, with how the business stands, the company's words, the timeline, and its peers, for Pro members.

Key facts on ZYME

Key facts on ZYME
The chartStronger than 85% of stocks above every average
Latest filing8-K, Oct 23 Signed a material agreement
1 more reason behind ZYME's 7, free with an account →3 more reasons behind ZYME's 7, for Pro members.

ZYME in the news

ReportReports Mon Nov 9, after the close. Every 3 months, a company tells everyone how much it sold and earned. It rose after 2 and fell after 2 of its last 4 reports, -4.1% on average. Past reports ›

Big story

Fri Oct 23: Deal

Zymeworks licenses experimental lung cancer drug to Roche in up to $813 million deal

ZYME closed −0.8% that day.

Reported by Reuters · covered by 6 outlets

What's next

Wed Nov 11: Stifel Healthcare Conference 2026Investor conference · date confirmed.

5 more dates ahead: conferences and the meeting, for Pro members.

Cash$322M, about 10 quarters (2.5 years) at the last year's spendingOn Jun 30 · the company says “beyond 2028”

ZYME catalysts

Coming up

After its last 4 reports it closed -4.1% on average, higher 2 of 4 times.

1 more coming up and 12 past catalysts since 2022, with sizes and sources, for Pro members.Get in free →

What's next for ZYME, and how long its cash lasts

Next step the company has named

2026“…diversify the foundation for projected durable revenue growth ZW191 & ZW251 Phase 1 trials initiated ZW209 IND anticipated in 2026 Pan-RAS ADC platform unveiled with three new candidates”Filing with regulators · SEC filing · Jun 29

What it means: a filing asks regulators to approve a drug for sale. Once it is complete and accepted, the FDA sets a decision date, and we show it here.

Lead program
ZW191 · Advanced Solid Tumors · Phase 1
Its trial
ZW191 in Participants With Solid TumorsPhase 1 · Active · 145 people · main data estimated Dec 2026 · NCT06555744

1 more trial, 2 more milestones and 48 filings, for Pro members.

Cash runway Jun 30 balance sheet

About 10 quarters

$322M in cash and investments (as the company counts them), at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money. The company's estimate is “beyond 2028” (8-K, Mar 2).

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed May 2, 2024)
  • At-the-market share sales program (424B5, filed Aug 2, 2024)

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

EVP, Head of R&D Adam Schayowitz sold 13,832 shares on Oct 9. 7 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Kenneth Galbraith’s 16 filings and quotes.

Get an alert when ZYME files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

11 more FDA dates and 102 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 143 dates, ranked →

Why ZYME scores 7

Averagefor quality, not price, 6 of 14 chart checks firingWhat the Quality Score means

Well above its recent run. ZYME scores 7 today, against a median of 3 over its last 20 recorded sessions.

  • +6Chart checks 6 of 14 firing right now, one point each
  • +3Long-term trend above a rising 200-⁠day average, near its 52-⁠week high
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Growth subtractsSales and margins against a year earlier: up to +3 for fast growth and widening margins, down to -2 when both shrink.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.
  • News adds

No effect today: Run-up, Size, Dilution, Volatility, Persistence, and Insider trades.

What every line is worth, and the reason behind it, on ZYME and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 4:03 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-⁠scored stocks returned 2.2x the average stock over the next month. How we tested it

Alert me when ZYME's Quality Score turns up

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  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

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ZYME has 6 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on ZYME, and all 14 on every stock.Get in free →

ZYME RSI today: 62.5, above its 50-day and 200-day averages

Not scored

Not in the Quality Score: over 20 years of tests, 2006 to 2026, they added no edge.

The deep dive on ZYME

4 more findings on ZYME, each with its source, for Pro membersGet in free →

How ZYME ranks in Pharma

ZYME is #22 of 92 by Quality Score.

How ZYME ranks in Pharma
22Zymeworks (ZYME) logoZYMEZymeworks7

Share count against a year before: ZYME -3.1%, NRIX +33%, IMNM +30%, PTCT +6.2%.

More in Pharma

When does ZYME report earnings, and what happens after?

Reports Mon Nov 9, after the close (in 7 days). Confirmed.

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What ZYME reported on Aug 6, 2026

The quarter

The figures are not read from the release yet.

“The decrease was driven mainly by absence of significant non-recurring collaboration revenue recognized in 2026, as well as continued declines in development support and drug supply revenue from Jazz.”

The filing on EDGAR

Where the sales came from

ZYME's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The change in 2026 was primarily due to a decrease in revenue, driven by the non-recurring clinical milestones earned in 2Q-2025 and interest expense related to the royalty-backed note financing arrangement with Royalty Pharma.”

From its results filing (SEC filing · Aug 6)

The numbers

Market value
$2.1B
today
Sales
$37.1M
down 69.8% on the year
Free cash flow
-$121M
last 12 months

Sales fell 36% a year over 3 years, fiscal 2022 to 2025.

Its share count grew 8.4% a year over 5 years.

3 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on ZYME: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.Get in free →
ReportedGapReaction5
sessions
Aug 6, 2026After close+4.2%+1.8%+11.4%
May 7, 2026After close-1.5%-10.2%-9.9%
Mar 2, 2026Before open-3.2%+0.1%+3.4%

ZYME closed higher after 2 of its last 4 reports.

All 4 reports, and ZYME's Quality Score going into each

Everyone reporting earnings next week

ZYME sales and profit by year

Sales and profit by year

Sales grew in three of the last five years, to $106M in 2025. It made a profit in one of the six years.

ZYME share count over time

3% fewer shares than a year earlier.

Weighted shares, quarter to Jun 30, 2026, both from one filing

Shares of ZYME outstanding, as filed
Shares
outstanding
As
of
71MAug 4, 2026
73MMay 6, 2026
73.7MFeb 26, 2026
74.8MNov 4, 2025
Offerings, shelves, and splits of ZYME, from its filings
From its
filings
Filed
Set up an at-the-market program for up to $150M of shares, about 7% of its market valueAug 2, 2024
Priced a sale of sharesMay 3, 2024
Set up an at-the-market program for up to $150M of shares, about 7% of its market valueMay 3, 2024
Registered shares for a later sale (S-3ASR)May 2, 2024

2 more offerings on file, for Pro members.

Insiders trading ZYME

ZYME insider trades

One insider sold $358K across 1 filing in the last 6 months. No open-⁠market buys on record. The newest:

SellAdam Schayowitz$358KEVP, Head of R&Dat $25.85 on Oct 9, filed Oct 9

ZYME's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold ZYME?

In ETFs: ZYME is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Zymeworks

Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.

264 employeesMiddletown, DEzymeworks.com

What Zymeworks says it competes with

“The biopharmaceutical industry is characterized by rapidly advancing technologies, intense competition and a strong emphasis on proprietary products.”

From its annual report, SEC filing · Mar 2, 2026

2 more sentences and what it says it does, for Pro membersGet in free →

ZYME's score card

Zymeworks (ZYME): Quality Score 7, Average, #22 of 92 in Pharma, with its price, on Breakaway
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  • What would move ZYME's score: 7 things
  • 9 more filings explained, a plain line each
  • Real-⁠time prices, no delay
BreakawayOct 9Adam Schayowitz sold ZYME$358K at $25.85, filed Oct 9

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See ZYME's 14 chart checks

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Straight Answers

As of Nov 2, 2026: ZYME's Quality Score is 7 (Average), #22 of 92 in Pharma. Insiders sold $358K in the last 6 months (Form 4).

Is ZYME a good stock to buy? What its Quality Score says

ZYME scores 7 today, which Breakaway calls Average. It is #22 of 92 in Pharma by Quality Score, with 6 of 14 chart checks firing. Up 309% over three years while the S&P 500 rose 89%. Cash lasts about 10 quarters at its spending (to Jun 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is ZYME's Quality Score?

ZYME scores 7 today, which Breakaway calls Average (6 to 10). That is #22 of 92 in Pharma by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind ZYME's 7.

Are insiders buying ZYME?

One insider sold $358K across 1 filing in the last 6 months. No open-⁠market buys on record. The newest is Adam Schayowitz, EVP, Head of R&D, who sold $358K on Oct 9.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

What's next for Zymeworks: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9 2026.

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