Lexicon Pharmaceuticals (LXRX) logo

Lexicon Pharmaceuticals (LXRX) stock

Close
$1.44
+1.41%

Medicines for diseases, market cap $659MSmall-cap biotech

After-hours $1.44 0.00%

As of 5:14 PM ET after-hours, delayed 15+ min · Live for Pro members

Why is LXRX down?

Down 39% in 3 months while the S&P 500 was flat.

  • It filed a prospectus for an offering of shares on Feb 2, 2026, its newest of 2 offering filings.

Sources: Price history, Oct 30, 2026; Prospectus supplement, Feb 2, 2026; Quarterly statements, Aug 6, 2026

−2Long-term trend below a falling 200-day average, down over two years

Tell me next time LXRX moves

Free account, no card. An optional alert when LXRX moves or its score changes.

Or see it live, free until Wednesday morning. No account.
1 more reason, free with an account →3 more reasons why LXRX is down, from its filings, with the other side, how the business stands, and the timeline, for Pro members.
Quality Score
-4
Poor
In its industry
#201of 291

LXRX's Quality Score rose 2 points on Mon, Nov 2, to -4.

Follow LXRX's trial news. Pro members can get an alert when Lexicon Pharmaceuticals files news, and see its trials, share raises, and its CEO's filings.

Get an alert when LXRX files news on its trialSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ4 2026“…the company's New Drug Application (NDA), which Lexicon anticipates will occur in the fourth quarter of 2026…”Filing with regulators · SEC filing · Aug 6
Cash$191M, about 11 quarters (3 years) at the last year's spendingOn Jun 30

Key facts on LXRX

Key facts on LXRX
Holding it backSales down 29% on the year
Latest filing10-Q, Aug 6 Filed its quarterly report (10-Q) for the quarter to Jun 30, 2026
1 more reason behind LXRX's -4, free with an account →3 more reasons behind LXRX's -4, for Pro members.

LXRX in the news

ReportReports Thursday, before the open. Every 3 months, a company tells everyone how much it sold and earned. It rose after 3 of its last 4 reports, +1.4% on average. Past reports ›

Tested. Our top-⁠scored stocks returned 2.2x the average stock over the next month. How we tested it

Cash$191M, about 11 quarters (3 years) at the last year's spendingOn Jun 30

LXRX catalysts

Coming up

After its last 4 reports it closed +1.4% on average, higher 3 of 4 times.

2 more coming up and 1 past catalyst since 2026, with sizes and sources, for Pro members.Get in free →

What's next for LXRX, and how long its cash lasts

Next step the company has named

Q4 2026“…support a resubmission of the company's New Drug Application (NDA), which Lexicon anticipates will occur in the fourth quarter of 2026 based on current estimated timing of data collection.”Filing with regulators · SEC filing · Aug 6

What it means: a filing asks regulators to approve a drug for sale. Once it is complete and accepted, the FDA sets a decision date, and we show it here.

A trial underway
SONATA-HCMPhase 3 · Active · 500 people · main data estimated Jan 2027 · NCT06481891

For Pro members: 2 more milestones and 35 filings.

Cash runway Jun 30 balance sheet

About 11 quarters

$191M in cash and short-term investments, at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money.

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3, filed Aug 2, 2024)
  • At-the-market share sales program (424B5, filed Nov 6, 2025)

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

Director Raymond Debbane bought 2,000 shares on Feb 25. 4 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Michael Exton’s 7 filings and quotes.

Get an alert when LXRX files news on its trialSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

11 more FDA dates and 102 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 143 dates, ranked →

Here is what Pro members see.

  • The same page for Pro members, on AMD

    Its Quality Score and rank, the line that drives it, and the live price.

  • The full chart

    A year of candles to start, out to the whole history, with insider trades marked and the Quality Score under the price.

  • Every line of the score

    Price action, the company, and signals, each with its points, on LXRX and every other stock.

  • FDA dates, counted down

    Each date in the company's words, its cash against the date, and an optional alert before it.

  • CEOs buying their own stock

    Every CEO buy, biggest names first. Sort, filter, save the list, and set optional alerts.

  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

  • The top 10, every day

    The ten highest Quality Scores at each close, kept day by day, week by week.

  • Optional alerts, your way

    Pick a stock, a score, a price, a filing, or a whole scan. It tells you by push or email.

  • Your watchlist, scored

    Your stocks by Quality Score, today's move, or name.

  • On your phone and your laptop

    The same account and watchlist on both, each laid out for its screen.

  • Prices refresh every 2.5 seconds during market hours.
  • Optional alerts by push, email, or the bell.
  • Add it to your Home Screen and it opens like an app.

LXRX has 2 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on LXRX, and all 14 on every stock.Get in free →

LXRX RSI today: 31.3, below its 50-day and 200-day averages

Not scored

Not in the Quality Score: over 20 years of tests, 2006 to 2026, they added no edge.

The deep dive on LXRX

6 more findings on LXRX, each with its source, for Pro membersGet in free →

How LXRX ranks in Biotech

LXRX is #201 of 291 by Quality Score.

How LXRX ranks in Biotech
201Lexicon Pharmaceuticals (LXRX) logoLXRXLexicon Pharmaceuticals-4

Share count against a year before: LXRX +20%, ACHV +170%, BHVN +47%, OCUL +30%.

More in Biotech

When does LXRX report earnings, and what happens after?

Reports Thu Nov 5, before the open (in 3 days). Confirmed.

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What LXRX reported on Aug 6, 2026

The quarter

The figures are not read from the release yet.

“Research and development expenses for the second quarter of 2026 increased to $17.4 million from $15.7 million for the corresponding period in 2025, reflecting higher external research expense in 2026 related to the Company’s ongoing SONATA-HCM Phase 3 clinical trial.”

The filing on EDGAR

Where the sales came from

LXRX's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

The numbers

Market value
$659M
today
Sales
$41.5M
down 29% on the year

Sales fell 9.1% a year over 10 years, fiscal 2015 to 2025.

4 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on LXRX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.Get in free →
ReportedGapReaction5
sessions
Aug 6, 2026Before open-20.0%-3.7%-4.1%
May 7, 2026Before open+3.1%+5.0%+52.5%
Mar 5, 2026Before open-5.5%+0.6%+5.5%

LXRX closed higher after 3 of its last 4 reports.

All 4 reports, and LXRX's Quality Score going into each

Everyone reporting earnings this week

LXRX sales and profit by year

Sales and profit by year

Sales grew in four of the last seven years, to $49.8M in 2025. It made a profit in one of the eight years.

LXRX share count over time

20% more shares than a year earlier.

Weighted shares, quarter to Jun 30, 2026, both from one filing

Shares of LXRX outstanding, as filed
Shares
outstanding
As
of
445MAug 3, 2026
444.2MMay 4, 2026
423.7MMar 4, 2026
363.4MNov 4, 2025
Offerings, shelves, and splits of LXRX, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3)Aug 6, 2026
Priced a sale of sharesFeb 2, 2026
Set up an at-the-market program for up to $75M of shares, about 11% of its market valueNov 6, 2025
Registered shares for a later sale (S-3)Aug 2, 2024

2 more offerings on file, for Pro members.

LXRX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

7 more officers and directors file at LXRX. Each page above names the rest.

See insider trades by person

Which ETFs hold LXRX?

In ETFs: LXRX is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Lexicon Pharmaceuticals

Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, and LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.

81 employeesThe Woodlands, TXlexpharma.com

What Lexicon Pharmaceuticals says it competes with

“The biotechnology and pharmaceutical industries are highly competitive and characterized by rapid technological change.”

From its annual report, SEC filing · Mar 5, 2026

2 more sentences and what it says it does, for Pro membersGet in free →

LXRX's score card

Lexicon Pharmaceuticals (LXRX): Quality Score -4, Poor, #201 of 291 in Biotech, with its price, on Breakaway
The picture a link to this page shows when it is shared.

Pro members see every line of every stock's score.

  • What would turn LXRX's score around: 9 things
  • 7 more filings explained, a plain line each
  • 4 more things pulling LXRX's score down
See LXRX's 14 chart checks

See it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

Straight Answers

As of Nov 2, 2026: LXRX's Quality Score is -4 (Poor), #201 of 291 in Biotech.

Is LXRX a good stock to buy? What its Quality Score says

LXRX scores -4 today, which Breakaway calls Poor. It is #201 of 291 in Biotech by Quality Score, with 2 of 14 chart checks firing. Down 39% in 3 months while the S&P 500 was flat. Cash lasts about 11 quarters at its spending (to Jun 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is LXRX's Quality Score?

LXRX scores -4 today, which Breakaway calls Poor (below zero). That is #201 of 291 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind LXRX's -4.

When does LXRX report earnings?

Reports Thu Nov 5, before the open, a date the company confirmed. LXRX closed higher after 3 of its last 4 reports. Past behavior, not a forecast.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

What's next for Lexicon Pharmaceuticals: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9 2026.

Breakaway publishes impersonal securities research and analytical tools: one formula, the same score for everyone. It is not personalized investment advice, and nothing here is a recommendation to buy or sell any security.

Market data from a licensed vendor. The age of every quote is shown on the page.

This browser is too old to show this page right. Update it, or open this page in Safari or Chrome.