CRISPR Therapeutics (CRSP) logo

CRISPR Therapeutics (CRSP) stock

Gene editing medicines , market cap $5.2B

Close
$49.99
-2.78%

After-hours $49.56 -0.86%

As of 7:03 PM ET after-hours, delayed 15+ min · Live for Pro members

Quality Score
-8
Poor
In its industry
#271of 291

CRSP's Quality Score rose 2 points on Mon, Nov 2, to -8.

Follow CRSP's trial news. Pro members can get an alert when CRISPR Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an alert when CRSP files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

Cash$2.4B, Over 5 years at the last year's spendingOn Jun 30

Why is CRSP down?

Down 46% over five years while the S&P 500 rose 76%.

  • It filed a prospectus for an at-the-market program for new shares of $600.0M on Oct 15, 2025.

Sources: Price history, Oct 30, 2026; Prospectus supplement, Oct 15, 2025; 10-K segment note, Feb 12, 2026

−3Insider trades the CEO is selling into the 52-week low: Samarth Kulkarni (Chief Executive Officer) sold $2.4M on Oct 19, and 3 more filings

1 more reason, free with an account →2 more reasons why CRSP lags the market, from its filings, with the other side, the timeline, and its peers, for Pro members.

Key facts on CRSP

Key facts on CRSP
Holding it backSales down 65% on the year
Latest filing8-K, Nov 2 Reported its quarterly results
1 more reason behind CRSP's -8, free with an account →5 more reasons behind CRSP's -8, for Pro members.

CRSP in the news

ReportToday after the close: sales of $12.7M; a loss of $1.15 a share. Past reports ›

Big story

Mon Oct 19: Leadership

CRISPR Therapeutics AG filed an 8-K reporting a change of CFO

CRSP closed −0.3% the next session (Oct 20).

From the company's SEC filing

What's next

Fri Nov 6: American Heart Association (AHA)…Industry event · date confirmed.

1 more date ahead: the conference, for Pro members.

Tested. Our top-⁠scored stocks returned 2.2x the average stock over the next month. How we tested it

Cash$2.4B, Over 5 years at the last year's spendingOn Jun 30

CRSP catalysts

Coming up

After its last 3 reports it closed +4.4% on average, higher 2 of 3 times.

16 past catalysts since 2018, with sizes and sources, for Pro members.Get in free →

What's next for CRSP, and how long its cash lasts

Its trials

A trial underway
Safety, Tolerability and Efficacy of CTX340 in Participants With HypertensionPhase 1/2 · Recruiting · 69 people · main data estimated Jul 1, 2028 · NCT07758634

6 more trials, 34 filings, for Pro members.

Cash runway Jun 30 balance sheet

Over 5 years

$2.4B in cash and short-term investments, at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money.

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

No shelf registration or at-the-market program on file in the last three years.

For Pro members: 3 raises and their amounts, and the share count against a year ago.

Insiders

CEO Samarth Kulkarni sold 47,837 shares on Oct 19. 21 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Samarth Kulkarni’s 29 filings and quotes.

Get an alert when CRSP files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

11 more FDA dates and 102 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 143 dates, ranked →

Here is what Pro members see.

  • The same page for Pro members, on AMD

    Its Quality Score and rank, the line that drives it, and the live price.

  • The full chart

    A year of candles to start, out to the whole history, with insider trades marked and the Quality Score under the price.

  • Every line of the score

    Price action, the company, and signals, each with its points, on CRSP and every other stock.

  • FDA dates, counted down

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  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

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CRSP has 2 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on CRSP, and all 14 on every stock.Get in free →

CRSP RSI today: 44.0, below its 50-day and 200-day averages

Not scored

Not in the Quality Score: over 20 years of tests, 2006 to 2026, they added no edge.

The deep dive on CRSP

  • What it does and how it makes money4 findings"We are also eligible to receive tiered royalties on the sales of certain products in the low to mid-single digits." (10-K for fiscal 2025)SEC filing · Feb 12, 2026
  • Where it stands1 findingFor Pro members1 finding on where CRSP stands: its cash, debt, and share count, for Pro members
  • What changed in its filings3 findings"In the past, when the market price of a stock has been volatile, holders of that stock have instituted securities class action litigation against the company that issued the stock." (10-K for fiscal 2025)SEC filing · Feb 12, 2026A new heading in its "Risk Factors" this year: "CASGEVY For SCD Has Received A Commissioner’s National Priority Voucher. The Benefits Of Such A Voucher, Including A Potentially Accelerated Timeline For Review Of Any [sBLA] Submission For CASGEVY For SCD By The FDA, May Not Be Able To Be Fully Realized." (10-K for fiscal 2025; not in fiscal 2024's)SEC filing · Feb 12, 2026, against the one of Feb 11, 2025
  • Who holds and trades it3 findingsFor Pro members3 findings on who holds and trades CRSP, for Pro members
  • Against its closest peers4 peersNet income over four quarters: CRSP -$451M, TARS -$46.5M, BEAM -$85.4M, KOD -$242M.
8 more findings on CRSP, each with its source, for Pro membersGet in free →

How CRSP ranks in Biotech

CRSP is #271 of 291 by Quality Score.

How CRSP ranks in Biotech
271CRISPR Therapeutics (CRSP) logoCRSPCRISPR Therapeutics-8

Net income over four quarters: CRSP -$451M, TARS -$46.5M, BEAM -$85.4M, KOD -$242M.

More in Biotech

When does CRSP report earnings, and what happens after?

Expected to report Mon Nov 9, after the close (in 7 days). Expected.

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What CRSP reported on Nov 2, 2026

The quarter

Sales of $12.7M; a loss of $1.15 a share, from $1.17.

“The increase in cash was primarily driven by net proceeds of $585.4 million from the issuance of convertible senior notes in March 2026, offset by operating expenses.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

CRSP's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “The increase in R&D expense was primarily attributable to an increase in external research and development expenses and sublicense fees, offset by a decrease in employee-related costs.”

From its results filing (SEC filing · Nov 2)

1 more sentence, for Pro members.

The numbers

Market value
$5.2B
today
Sales
$13.4M
down 64.8% on the year
Free cash flow
-$371M
last 12 months

Its share count grew 6.4% a year over 5 years.

3 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on CRSP: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.Get in free →
ReportedGapReaction5
sessions
Aug 3, 2026After close+2.0%+7.1%+8.0%
May 4, 2026After close-1.8%-2.2%+0.8%
Feb 12, 2026After close+1.7%+8.5%+9.3%

CRSP closed higher after 2 of its last 3 reports.

Everyone reporting earnings next week

CRSP sales and profit by year

Sales and profit by year

Sales grew in three of the last seven years, to $3.5M in 2025. It made a profit in two of the eight years.

CRSP share count over time

11% more shares than a year earlier.

Weighted shares, quarter to Jun 30, 2026, both from one filing

Shares of CRSP outstanding, as filed
Shares
outstanding
As
of
96.7MJul 31, 2026
96.4MApr 30, 2026
96MFeb 10, 2026
95.3MNov 6, 2025
Offerings, shelves, and splits of CRSP, from its filings
From its
filings
Filed
Set up an at-the-market program for up to $600M of shares, about 11% of its market valueOct 15, 2025
Priced a sale of sharesMay 19, 2025
Registered shares for a later sale (S-3ASR)Aug 5, 2024
Priced a sale of sharesFeb 13, 2024

Insiders trading CRSP

CRSP insider trades

4 insiders sold $3.6M across 5 filings in the last 6 months. No open-⁠market buys on record. The newest:

SellSamarth Kulkarni$2.4MChief Executive Officerat $49.78 on Oct 19, filed Oct 20
All 5 insider filings on CRSP from the last six months, for Pro members.Get in free →

All CRSP insider trades

CRSP's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

About CRISPR Therapeutics

Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.

393 employeesZugcrisprtx.com

What CRISPR Therapeutics says it competes with

“The biotechnology and pharmaceutical industries, including in the gene editing, gene therapy, nucleic acids therapies, and cell therapy fields, are characterized by rapidly advancing technologies, intense competition and a strong emphasis on intellectual property and proprietary products.”

From its annual report, SEC filing · Feb 12, 2026

1 more sentence and what it says it does, for Pro membersGet in free →

CRSP's score card

CRISPR Therapeutics (CRSP): Quality Score -8, Poor, #271 of 291 in Biotech, with its price, on Breakaway
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Pro members see every line of every stock's score.

  • What would turn CRSP's score around: 9 things
  • 7 more filings explained, a plain line each
  • 6 more things pulling CRSP's score down
BreakawayOct 20Samarth Kulkarni sold CRSP$2.4M at $49.78, filed Oct 20

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See CRSP's 14 chart checks

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Straight Answers

As of Nov 2, 2026: CRSP's Quality Score is -8 (Poor), #271 of 291 in Biotech. Insiders sold $3.6M in the last 6 months (Form 4).

Is CRSP a good stock to buy? What its Quality Score says

CRSP scores -8 today, which Breakaway calls Poor. It is #271 of 291 in Biotech by Quality Score, with 2 of 14 chart checks firing. Down 46% over five years while the S&P 500 rose 76%. Cash lasts over 5 years at its spending (to Jun 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is CRSP's Quality Score?

CRSP scores -8 today, which Breakaway calls Poor (below zero). That is #271 of 291 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind CRSP's -8.

Are insiders buying CRSP?

4 insiders sold $3.6M across 5 filings in the last 6 months. No open-⁠market buys on record. The newest is Samarth Kulkarni, Chief Executive Officer, who sold $2.4M on Oct 19. Every filing, with the scored weight, for Pro members.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

What's next for CRISPR Therapeutics: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9 2026.

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