Axsome Therapeutics (AXSM) logo

Axsome Therapeutics (AXSM) stock

Nervous system therapies , market cap $7.5B

Close
$136.01
-5.83%

After-hours $135.50 -0.37%

As of 6:23 PM ET after-hours, delayed 15+ min · Live for Pro members

Why is AXSM down?

Down 32% in 3 months while the S&P 500 was flat.

  • Its filed figures improved while the shares fell.

No filing or news in our sources explains it.

Sources: Price history, Oct 30, 2026; Annual reports, Dec 31, 2025

−1Long-term trend below a falling 200-day average

Tell me next time AXSM moves

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1 more reason, free with an account →1 more reason why AXSM is down, from its filings, with the other side, how the business stands, and the timeline, for Pro members.
Quality Score
3
Below Average
In its industry
#81of 291

AXSM's Quality Score fell 1 point on Mon, Nov 2, to 3.

Follow AXSM's trial news. Pro members can get an alert when Axsome Therapeutics files news, and see its trials, share raises, and its CEO's filings.

Get an alert when AXSM files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ1 2027“…in the trial has been reached, and the Company anticipates topline results in the first quarter of 2027…”Trial data · SEC filing · Nov 2
Cash$320M in cash. One of the last four quarters brought cash in while the others used it.On Jun 30

Key facts on AXSM

Key facts on AXSM
Holding it backFree cash flow -$72M on $777M of sales
Latest filing8-K, Nov 2 Reported its quarterly results
1 more reason behind AXSM's 3, free with an account →3 more reasons behind AXSM's 3, for Pro members.

AXSM in the news

ReportThis morning: sales of $259.7M; a loss of $0.25 a share. Past reports ›

In the newsAxsome Therapeutics (AXSM) Reports Q3 Loss, Tops Revenue Estimates Yahoo Finance and 2 more · 7:13 AM ET

What's next

Expected to report Mon Feb 22, before the open

After its last 4 reports it closed +0.4% on average, higher 2 of 4 times.

Tested. Our top-⁠scored stocks returned 2.2x the average stock over the next month. How we tested it

Cash$320M in cash. One of the last four quarters brought cash in while the others used it.On Jun 30

AXSM catalysts

Coming up
4 more coming up and 5 past catalysts since 2020, with sizes and sources, for Pro members.Get in free →

What's next for AXSM, and how long its cash lasts

Next step the company has named

Q1 2027“Target enrollment in the trial has been reached, and the Company anticipates topline results in the first quarter of 2027.”Trial data · SEC filing · Nov 2

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work DisorderPhase 3 · Recruiting · 520 people · main data estimated Dec 2026 · NCT06568367

10 more trials, 1 with data due this year, 4 more milestones and 50 filings, for Pro members.

Cash runway Jun 30 balance sheet

$320M in cash

One of the last four quarters brought cash in while the others used it, so an average says little about the next.

What it means: a runway is counted only when each of the last four quarters used cash.

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Nov 3, 2025)
  • At-the-market share sales program (S-3ASR, filed Nov 3, 2025)

For Pro members: the amounts, and the share count against a year ago.

Insiders

Chief Operating Officer Mark L. Jacobson sold 10,000 shares on Sep 3, under a planned sale. 16 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Herriot Tabuteau’s 20 filings and quotes.

Get an alert when AXSM files news on its trialsSee it live, free until Wednesday morning. No account. No card. Then keep going with a free account.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

11 more FDA dates and 102 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 143 dates, ranked →

Here is what Pro members see.

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  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

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AXSM has 2 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on AXSM, and all 14 on every stock.Get in free →

AXSM RSI today: 20.0, below its 50-day and 200-day averages

Not scored

Not in the Quality Score: over 20 years of tests, 2006 to 2026, they added no edge.

The deep dive on AXSM

8 more findings on AXSM, each with its source, for Pro membersGet in free →

How AXSM ranks in Biotech

AXSM is #81 of 291 by Quality Score.

How AXSM ranks in Biotech
81Axsome Therapeutics (AXSM) logoAXSMAxsome Therapeutics3

Sales over four quarters against a year before: AXSM +57%, TNGX +121%, TVTX +77%.

More in Biotech

When does AXSM report earnings, and what happens after?

Expected to report Mon Feb 22, before the open (in 112 days). Expected.

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What AXSM reported on Nov 2, 2026

The quarter

Sales of $259.7M, 52% more than a year ago; a loss of $0.25 a share, from $0.94.

“The increase primarily reflects commercialization activities for AUVELITY and SYMBRAVO.”

The quarter that ended Sep 30, from the company's press release

The press releaseThe filing on EDGAR

Where the sales came from

AXSM's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “We expect sustained momentum driven by strong underlying demand for Auvelity in major depressive disorder, and continued acceleration of new patient initiations in Alzheimer’s disease agitation”

From its results filing (SEC filing · Nov 2)

1 more sentence, for Pro members.

The numbers

Market value
$7.5B
today
Sales
$777M
up 56.9% on the year
Free cash flow
-$72M
last 12 months

Sales grew 134% a year over 3 years, fiscal 2022 to 2025.

Its share count grew 7% a year over 3 years.

4 more figures, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on AXSM: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.Get in free →
ReportedGapReaction5
sessions
Nov 2, 2026Before open-5.0%-5.8%open
Aug 10, 2026Before open+1.5%+3.8%+0.4%
May 4, 2026Before open+2.6%+8.3%+5.3%

AXSM closed higher after 2 of its last 4 reports.

All 4 reports, and AXSM's Quality Score going into each

AXSM sales and profit by year

Sales and profit by year

Sales grew every year from 2022 to 2025, to $638M. It lost money in each of the four years.

AXSM share count over time

Shares: 4.8% more than a year ago (to Jun 30).

Shares of AXSM outstanding, as filed
Shares
outstanding
As
of
52.4MAug 3, 2026
51.5MApr 27, 2026
51.2MFeb 16, 2026
50.4MOct 27, 2025
Offerings, shelves, and splits of AXSM, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Nov 3, 2025

AXSM's officers and directors

Officers and directors with a Form 4 in the last 12 months.

See insider trades by person

Which ETFs hold AXSM?

In ETFs: AXSM is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Axsome Therapeutics

Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options. Its pipeline products include AXS-05, AXS-07, AXS-12, and AXS-14. It manages its business as one operating segment and reporting unit, which is the business of developing and delivering novel therapies for the management of CNS disorders.

925 employeesNew York, NYaxsome.com

What Axsome Therapeutics says it competes with

“Our industry is highly competitive and subject to rapid and significant technological change.”

From its annual report, SEC filing · Feb 23, 2026

2 more sentences and what it says it does, for Pro membersGet in free →

AXSM's score card

Axsome Therapeutics (AXSM): Quality Score 3, Below Average, #81 of 291 in Biotech, with its price, on Breakaway
The picture a link to this page shows when it is shared.

Pro members see every line of every stock's score.

  • What would turn AXSM's score around: 7 things
  • 3 more filings explained, a plain line each
  • 2 more things pulling AXSM's score down
See AXSM's 14 chart checks

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Straight Answers

As of Nov 2, 2026: AXSM's Quality Score is 3 (Below Average), #81 of 291 in Biotech.

Is AXSM a good stock to buy? What its Quality Score says

AXSM scores 3 today, which Breakaway calls Below Average. It is #81 of 291 in Biotech by Quality Score, with 2 of 14 chart checks firing. Down 32% in 3 months while the S&P 500 was flat. Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is AXSM's Quality Score?

AXSM scores 3 today, which Breakaway calls Below Average (0 to 5). That is #81 of 291 in Biotech by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind AXSM's 3.

When does AXSM report earnings?

Expected to report Mon Feb 22, before the open, a date Breakaway expects from the company's usual timing; the company has not confirmed it. AXSM closed higher after 2 of its last 4 reports. Past behavior, not a forecast.

Are the prices delayed?

Only on the public pages, which run at least 15 minutes behind. Pro members, and anyone on a guest pass, see real-time prices: the scanner refreshes every 15 seconds, and your watchlist every few seconds, pre-market and after hours included.

What's next for Axsome Therapeutics: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9 2026.

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