Annexon (ANNX) logo

Annexon (ANNX) stock

$4.21
-0.47%

Complement disease medicines, worth $759MSmall-cap biotech

As of Tuesday's close · Live for Pro members at the open

Quality Score
-6
Poor
In its industry
#84of 90
Checks firing
1of 14
Choppy
From 52-week high
-41.4%
under its best in a year

ANNX's Quality Score fell 1 point on Tue, Nov 10, to -6. It did not trade higher than the day before.

Follow ANNX's trial news. Pro members can get an alert when Annexon files news, and see its trials, share raises, and its CEO's filings.

Get an alert when ANNX files news on its trialsSee it live, free until Thursday morning. No account. No card. Then keep going with a free account.

We do the work for you. Every stock is scored and ranked, every 15 seconds while the market is open. Here it's 15 minutes behind. Pro members see it live.

NextQ4 2026“…(DMC) will assess the ARCHER II single study Month 15 primary endpoint in the fourth quarter of 2026…”Trial data · SEC filing · Nov 9
Cash$213M, about 4 quarters at the last year's spendingOn Sep 30 · the company says “into 2028”

Why ANNX rose on Oct 19

Up 18% on Oct 19, and still 24% over its Oct 16 close.

  • Annexon rose 18% that day while small-cap biotech stocks rose a median 2%: it beat its group by 16 points.

Sources: Price history, Oct 19, 2026

The other side, the timeline, and its peers, for Pro members.

Key facts on ANNX

Key facts on ANNX
Holding it back37.2% more shares than a year ago
Latest filing8-K, Nov 9 Reported its quarterly results
1 more reason behind ANNX's -6, free with an account →3 more reasons behind ANNX's -6, for Pro members.

ANNX in the news

ReportLast night: the results are out. Past reports ›

Cash$213M, about 4 quarters at the last year's spendingOn Sep 30 · the company says “into 2028”

ANNX catalysts

Coming up

After its last 4 reports it closed +3.5% on average, higher 2 of 4 times.

3 more coming up, with sizes and sources, for Pro members.

What's next for ANNX, and how long its cash lasts

Next step the company has named

Q4 2026“An independent Data Monitoring Committee (DMC) will assess the ARCHER II single study Month 15 primary endpoint in the fourth quarter of 2026.”Trial data · SEC filing · Nov 9

What it means: the first look at a trial’s main results, as the company reports them.

A trial underway
Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)Phase 3 · Recruiting · 30 people · main data estimated May 31, 2027 · NCT07020819

2 more trials, 2 more milestones and 38 filings, for Pro members.

Cash runway Sep 30 balance sheet

About 4 quarters

$213M in cash and short-term investments, at its spending over the last year

What it means: how long the cash would last at the same pace, before any new money. The company's estimate is “into 2028” (8-K, Nov 9).

For Pro members: the cash used each quarter, and the math.

Dilution on the horizon

  • Shelf registration (S-3ASR, filed Mar 31, 2026)
  • At-the-market share sales program (S-3ASR, filed Mar 31, 2026)

For Pro members: 4 raises and their amounts, and the share count against a year ago.

Insiders

CEO Douglas Love bought 26,065 shares on Sep 24. 14 more insider trades this year.

From Form 4: open-market buys and sales only.

For Pro members: every trade, and Douglas Love’s 14 filings and quotes.

See every upcoming FDA date →

FDA dates in the next 60 days

Decision dates and advisory committee meetings the companies have announced in their filings, soonest first and small companies first.

DateStockDrug

14 more FDA dates and 103 trial data dates in the next 60 days, each on the FDA calendar. Pro members see whether each company's cash lasts past its date, with an optional alert before it. See all 151 dates, ranked →

Why ANNX scores -6

Poorfor quality, not price, 1 of 14 chart checks firingWhat the Quality Score means

-6 is below -5, off the left end of the scale.

  • −2Long-term trend below a falling 200-⁠day average, down over two years
  • −2Dilution 37.2% more shares outstanding than a year agoNew shares over the year: -1 at 10% more, -2 at 25% more.
  • Chart checks adds
  • Profit subtractsRead on the last four quarters against the four before, or the last full year where no quarters are filed.
  • Volatility subtractsA daily range of 5% or more with nothing behind it (no profit or cash flow, sales shrinking, or 10% more shares outstanding with no free cash flow): -1, or -2 from 8%.
  • Cash flow subtracts-1 when free cash flow over the last four quarters is negative.

No effect today: Run-up, Size, Growth, Persistence, News, and Insider trades.

What every line is worth, and the reason behind it, on ANNX and every other stock.Get in free →

Price, score, chart checks, and the industry rank are from a snapshot taken at 11:29 PM ET, at least 15 minutes behind. How we rank stocks.

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

How ANNX ranks in Pharma

ANNX is #84 of 90 by Quality Score.

How ANNX ranks in Pharma
RankStockQuality Score
84Annexon (ANNX) logoANNXAnnexon-6

Share count against a year before: ANNX +37%, LXRX +22%.

More in Pharma

When does ANNX report earnings, and what happens after?

Expected to report Mon Mar 29, after the close (in 139 days).

What an earnings report is: every 3 months, a company tells everyone how much it sold and earned. We read the figures, the outlook, and how the stock moved after.

What ANNX reported on Nov 9, 2026

The quarter

The figures are not read from the release yet.

“The change in G&A expenses reflects ongoing corporate consulting and professional services costs for the advancement of our registrational programs and compensation and personnel-related expenses.”

The filing on EDGAR

Where the sales came from

ANNX's results filing gives no sales by line in a table we read.

The outlook

No outlook figures read from this release.

In the company's words

  • “Next Milestone: EMA review of MAA underway; BLA submission with U.S./European data from FORWARD expected fourth quarter of 2026.”

From its results filing (SEC filing · Nov 9)

1 more sentence, for Pro members.

The numbers

Market value
$759M
today
Free cash flow
-$190M
last 12 months

1 more figure, for Pro members.

No analyst estimates on Breakaway: every figure here is filed.

The whole report on ANNX: every line of its sales, every outlook beside the one it replaced, and the company's words, for Pro members.

Close after the report, last 3

+3.1%-0.2%-0.5%
May 7Aug 12Nov 9
ReportedGapReaction5
days
Nov 9, 2026After close+1.6%-0.5%not yet
Aug 12, 2026Before open-5.2%-0.2%-1.1%
May 7, 2026After close+1.7%+3.1%-2.7%

ANNX closed higher after 2 of its last 4 reports.

All 4 reports, and ANNX's Quality Score going into each

ANNX has 1 of 14 chart checks firing

Volume1 of 3 shown
Tight range1 of 3 shown
Buying1 of 3 shown
The other 10 checks on ANNX, and all 14 on every stock.Get in free →

ANNX RSI today: 54.7, above its 50-day, below its 200-day

Not scored

RSI 54.7, MACD above signal, above its 50-day, below its 200-day. Not scored.

The deep dive on ANNX

6 more findings on ANNX, each with its source, for Pro members.

ANNX share count over time

37% more shares than a year earlier.

Weighted shares, quarter to Sep 30, 2026, both from one filing

Shares of ANNX outstanding, as filed
Shares
outstanding
As
of
38.6MMay 2, 2022
38.6MFeb 25, 2022
38.4MOct 29, 2021
38.3MAug 10, 2021
Offerings, shelves, and splits of ANNX, from its filings
From its
filings
Filed
Registered shares for a later sale (S-3ASR)Mar 31, 2026
Raised $65.2M in a sale of shares, about 9% of its market valueNov 13, 2025
Registered shares for a later sale (S-3)Aug 12, 2024
Raised $81.3M in a sale of shares, about 11% of its market valueJun 7, 2024

3 more offerings on file, for Pro members.

ANNX insider trades

2 insiders bought $3.4M across 2 filings in the last 6 months. No open-⁠market sales on record. The newest:

BuyDouglas Love$100KPresident and CEOat $3.83 on Sep 24, filed Sep 25

ANNX's officers and directors

Officers and directors with a Form 4 in the last 12 months.

One more officer or director files at ANNX.

See insider trades by person

Which ETFs hold ANNX?

In ETFs: ANNX is under 0.1% of VTI, the most of the 24 funds Breakaway covers, by their holdings as filed for Jun 30, 2026.

About Annexon

Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.

92 employeesBrisbane, CAannexonbio.com

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    Every CEO buy, biggest names first. Sort, filter, save the list, and set optional alerts.

  • Congress trades

    A member's trades, newest first, each with its amount. Sort and filter the whole list.

  • 14 chart checks, read for you

    The ones firing on the stock, each in plain words, its rule a tap away.

  • Earnings, week by week

    Who reports each day, and how each stock took its last four reports.

  • The market map

    Every stock a box, colored by its Quality Score.

  • Themes, ranked live

    Each theme's stocks ranked by Quality Score, live. Here, AI chips.

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Pro members see every line of every stock's score.

  • What would turn ANNX's score around: 8 things
  • 8 more filings explained, a plain line each
  • Real-⁠time prices, no delay
BreakawaySep 25Douglas Love bought ANNX$100K at $3.83, filed Sep 25

Alerts are optional.

See ANNX's 14 chart checks

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Straight AnswersStraight Answers

As of Nov 10, 2026: ANNX's Quality Score is -6 (Poor), #84 of 90 in Pharma. Insiders bought $3.4M in the last 6 months (Form 4).

What does ANNX's Quality Score say?

ANNX scores -6 today, which Breakaway calls Poor. It is #84 of 90 in Pharma by Quality Score, with 1 of 14 chart checks firing. Up 18% on Oct 19, and still 24% over its Oct 16 close. Cash lasts about 4 quarters at its spending (to Sep 30). Breakaway does not say whether to buy any stock: the score does not know your situation, and it is not a recommendation to buy or sell anything. Please do your own research.

What is ANNX's Quality Score?

ANNX scores -6 today, which Breakaway calls Poor (below zero). That is #84 of 90 in Pharma by Quality Score. The score adds up the chart checks, the trend, the company's filed sales, its profits, the news, insider trades, and Congress trades. The section above lists the lines behind ANNX's -6.

Are insiders buying ANNX?

2 insiders bought $3.4M across 2 filings in the last 6 months. No open-⁠market sales on record. The newest is Douglas Love, President and CEO, who bought $100K on Sep 24. Every filing, with the scored weight, for Pro members.

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What's next for Annexon: from its SEC filings and ClinicalTrials.gov, the company's words, the registry's dates, and arithmetic, not a forecast. Companies often miss the dates they set.

The moves after past earnings reports are past behavior, not a forecast.

The price, the score, the chart checks and readings, and the industry rank on this page are delayed at least 15 minutes.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

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