Parabilis Medicines (PBLS) logo

Parabilis Medicines' IPO

Parabilis Medicines · Filed May 19 · Nasdaq · Form S-1

Listed Jun 10, 2026 at $20 on Nasdaq as PBLS. Today 43% above its $20 offer price; its first day closed +58.0%.

Offer price: $20, a share
Market cap: $2.33B, from its filing
Shares: 33,500,000, offered

From its final prospectus (424B4) on SEC EDGAR.

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What does Parabilis Medicines do?

Parabilis Medicines' facts, each with its source
FactParabilis
Medicines
What it does“We are a clinical-stage biopharmaceutical company built to develop transformative medicines addressing some of the most consequential, yet historically undruggable, protein targets driving human disease.”From its final prospectus (424B4) of Jun 10, 2026
Founded2015From its final prospectus (424B4) of Jun 10, 2026
IncorporatedDelaware, 2015From its final prospectus (424B4) of Jun 10, 2026
HeadquartersCambridge, MassachusettsFrom its final prospectus (424B4) of Jun 10, 2026
Employees145 full-time, as of April 1, 2026From its final prospectus (424B4) of Jun 10, 2026
Websiteparabilismed.comFrom its final prospectus (424B4) of Jun 10, 2026

What is the offering?

Each figure names the filing it is from and that filing's date. The market cap is Breakaway's arithmetic from the prospectus's share count.

Parabilis Medicines' facts, each with its source
FactParabilis
Medicines
Shares offered33,500,000From the final prospectus (424B4) filed Jun 10, 2026
Offer price$20 a shareFrom the final prospectus (424B4) filed Jun 10, 2026
Raised at that price$670 millionFrom the final prospectus (424B4) filed Jun 10, 2026
Underwriters' discount$46.9 millionFrom the final prospectus (424B4) filed Jun 10, 2026
Net proceeds the company expectsAbout $618 millionFrom the final prospectus (424B4) filed Jun 10, 2026
Underwriters' option5,025,000 more sharesFrom the final prospectus (424B4) filed Jun 10, 2026
UnderwritersLeerink Partners, BofA Securities, Evercore ISI, Guggenheim Securities, and LifeSci CapitalFrom the final prospectus (424B4) filed Jun 10, 2026, as its cover names them
ExchangeNasdaq Global Select Market, as PBLSFrom the final prospectus (424B4) filed Jun 10, 2026
Shares outstanding after116,564,570From the final prospectus (424B4) filed Jun 10, 2026
Market cap at the offer price$2.33 billionBreakaway's arithmetic from the prospectus's share count

What the filing says about its money

Parabilis Medicines' facts, each with its source
FactParabilis
Medicines
RevenueNone from product sales yetFrom its final prospectus (424B4) of Jun 10, 2026: it has not generated any product revenue
Net loss$146 million, year to December 31, 2025From its final prospectus (424B4) of Jun 10, 2026, its summary financial data
Last preferred stockSeries F preferredFrom its final prospectus (424B4) of Jun 10, 2026
Raised before the IPO$877 million in private financingsFrom its final prospectus (424B4) of Jun 10, 2026

What risks does Parabilis Medicines name first?

  1. “We are a clinical-stage biotechnology company with a limited operating history and no products approved by regulators for commercial sale, which may make it difficult to evaluate our current and future business prospects.”
  2. “Even if this offering and the concurrent private placement are completed, we will require substantial additional capital to finance our operations in the future.”
  3. “We have incurred significant losses since our inception and anticipate that we will continue to incur significant losses for the foreseeable future.”

The first three of the risks its prospectus summary lists, in the company's words. The rest, and each in full, are in the filing. Read the filing.

Dates so far

Parabilis Medicines' IPO dates, each with its source
WhatDay
Registration filedForm S-1, SEC EDGARMay 19, 2026
Exchange registration filedexchange registration (Form 8-A), SEC EDGARJun 5, 2026
Declared effective by the SECSEC notice of effectiveness, SEC EDGARJun 9, 2026
Pricedfinal prospectus (424B4), filed Jun 10, SEC EDGARJun 9, 2026
First tradeMassive's IPO calendarJun 10, 2026
Lock-up endsfinal prospectus, SEC EDGAR: “180 days from the date of this prospectus”Dec 6, 2026

How did its first days trade?

From its daily bars, each close against its $20 offer price.

Parabilis Medicines' first sessions
DayOpenCloseFrom the
offer
Jun 10$33.35$31.60+58.0%
Jun 11$30$30.31+51.5%
Jun 12$29.86$27.26+36.3%
Jun 15$26.80$25.01+25.1%
Jun 16$25.26$26.59+32.9%

What is Parabilis Medicines' Quality Score?

2

Below Average

105 trading days so far; 3 of the 14 checks wait for more history.

PBLS's page, with every reason behind its score

Tested. Our top-scored stocks returned 2.2x the average stock over the next month. Reconstructed after the fact; recorded live since Sep 9, 2026. How we tested it

The other IPOs expected

The other IPOs expected or in registration
CompanyPrice

Parabilis Medicines IPO questions

When is Parabilis Medicines' IPO?

Listed Jun 10, 2026 at $20 on Nasdaq as PBLS.

What is Parabilis Medicines' IPO price?

Parabilis Medicines' IPO priced at $20 a share, per its final prospectus of Jun 10, 2026.

How many shares is Parabilis Medicines selling?

33,500,000 shares, and the underwriters may buy 5,025,000 more, per its final prospectus (424B4).

Who are the underwriters?

Leerink Partners, BofA Securities, Evercore ISI, Guggenheim Securities, and LifeSci Capital, as the prospectus's cover names them.

When does the lock-up end?

Parabilis Medicines' IPO lock-⁠up ends Dec 6, 2026. Its final prospectus says: “180 days from the date of this prospectus.”

Does Breakaway rate Parabilis Medicines?

Parabilis Medicines has a Quality Score of 2 today. The score counts the 14 chart checks and the company's filings; a check that needs more history than a new stock has waits for it.

Can Breakaway say where Parabilis Medicines' price will go?

No. Breakaway does not say where a price will go. Every figure here is from the company's SEC filings, linked on each line.

Where every figure comes from: how the IPO pages are made.

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Sources: Parabilis Medicines, Inc.'s final prospectus (424B4) of Jun 10, 2026; the prices, the stock's daily bars, 15 minutes behind.

Not advice. Figures from each company's SEC filings, linked on each line. Breakaway is not an underwriter, broker, or adviser, and does not say where a price will go.

Scores as of 9:27 AM ET, 15 minutes behind.

Our top-scored stocks' record: Oct 2021 to Sep 2026, before costs. Recorded live since Sep 9, 2026.

Breakaway publishes impersonal securities research and analytical tools: one formula, the same score for everyone. It is not personalized investment advice, and nothing here is a recommendation to buy or sell any security.

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